Prediagnostic presentations of glioma in primary care: a case–control study

Q1 Medicine CNS Oncology Pub Date : 2019-11-01 DOI:10.2217/cns-2019-0015
Marthe C. M. Peeters, L. Dirven, J. Koekkoek, M. Numans, M. Taphoorn
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引用次数: 3

Abstract

Aim: This study aimed to assess the prevalence of symptoms glioma patients may present with to the general practitioner, and whether these can be distinguished from patients with other CNS disorders or any other condition. Methods: Glioma patients were matched to CNS patients and ‘other controls’ using anonymized general practitioner registries. Prevalences were evaluated in the 5 years prior to diagnosis. Result: CNS patients reported significantly more motor symptoms in the period 60–24 months, (p = 0.039). Moreover, <6 months before diagnosis CNS patients differed significantly in mood disorders/fear compared with ‘other controls’ (p = 0.012) but not glioma patients (p = 0.816). Conclusion: Glioma patients could not be distinguished from both control groups with respect to the number or type of prediagnostic symptoms.
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初级保健中胶质瘤的诊断前表现:一项病例对照研究
目的:本研究旨在评估神经胶质瘤患者向全科医生可能出现的症状的患病率,以及这些症状是否可以与其他中枢神经系统疾病或任何其他疾病的患者区分开来。方法:使用匿名全科医生注册将胶质瘤患者与中枢神经系统患者和“其他对照组”进行匹配。在诊断前5年评估患病率。结果:中枢神经系统患者在60-24个月期间报告的运动症状显著增加(p = 0.039)。此外,在诊断前<6个月,中枢神经系统患者的情绪障碍/恐惧与“其他对照组”相比有显著差异(p = 0.012),但胶质瘤患者没有差异(p = 0.816)。结论:胶质瘤患者在诊断前症状的数量和类型上无法与对照组区分。
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来源期刊
CNS Oncology
CNS Oncology Medicine-Neurology (clinical)
CiteScore
3.80
自引率
0.00%
发文量
12
审稿时长
13 weeks
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