Junguo Ran , Li Gou , Yan Liu , Changqiong Zheng , Fangqiong Tang
{"title":"The process of immobilizing enzyme of glucose sensor based on diamond film","authors":"Junguo Ran , Li Gou , Yan Liu , Changqiong Zheng , Fangqiong Tang","doi":"10.1016/S0968-5677(98)00106-0","DOIUrl":null,"url":null,"abstract":"<div><p>Considering the poor adhesion of electrode to substrate, diamond film as a new kind of substrate material was used to fabricate a glucose sensor. Particularly, the immobilizing enzyme was investigated in detail. SEM and XPS were chosen to identify whether organic functional groups were grafted to electrode surface or not. The response characteristics of a diamond film glucose sensor show that this glucose sensor has good properties in the linear range 0.5–11.4<!--> <!-->mM<!--> <!-->l<sup>-1</sup>, sensitivity 4.0<!--> <!-->nA<!--> <!-->mM<sup>-1<!--> </sup>mm<sup>-2</sup> and peak reaction speed 2.5<!--> <!-->μA. The glucose sensor based on diamond film was a novel microchip glucose sensor with good potential.</p></div>","PeriodicalId":22050,"journal":{"name":"Supramolecular Science","volume":"5 5","pages":"Pages 699-700"},"PeriodicalIF":0.0000,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0968-5677(98)00106-0","citationCount":"7","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Supramolecular Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0968567798001060","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"1999/2/16 0:00:00","PubModel":"Epub","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 7
Abstract
Considering the poor adhesion of electrode to substrate, diamond film as a new kind of substrate material was used to fabricate a glucose sensor. Particularly, the immobilizing enzyme was investigated in detail. SEM and XPS were chosen to identify whether organic functional groups were grafted to electrode surface or not. The response characteristics of a diamond film glucose sensor show that this glucose sensor has good properties in the linear range 0.5–11.4 mM l-1, sensitivity 4.0 nA mM-1 mm-2 and peak reaction speed 2.5 μA. The glucose sensor based on diamond film was a novel microchip glucose sensor with good potential.
考虑到电极与衬底的附着力差，采用金刚石薄膜作为一种新型衬底材料制作葡萄糖传感器。特别对固定化酶进行了详细的研究。采用SEM和XPS检测电极表面是否接枝有机官能团。金刚石膜葡萄糖传感器的响应特性表明，该传感器在0.5 ~ 11.4 mM l-1线性范围内具有良好的性能，灵敏度为4.0 nA mM-1 mM- 2，峰值反应速度为2.5 μA。基于金刚石薄膜的葡萄糖传感器是一种极具发展潜力的新型微芯片葡萄糖传感器。
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