Correlation between CT finding and mediastinoscopic biopsy results for diagnosis of mediastinal lymphadenopathy

Lamiaa Agwa, Hosny El-Sallab, M. Ahmed, Wasiem Mohammad
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Abstract

Background Mediastinal lesions are difficult to detect on radiograph because these lesions are of soft tissue densities and are surrounded by soft tissue structures. Here is where computed tomography (CT) can provide the answer. It provides information on the anatomical extent of the lesion and the nature of the lesion. Aim The aim of this work is to evaluate the possibility of anticipation of histopathological tissue diagnosis for a mediastinal lymphadenopathy specimen taken by mediastinoscopy on the basis of preoperative CT findings for patients admitted in Al-Zahraa University Hospital in the Cardiothoracic Surgery Department. Patients and methods Thirty patients were included in this study, admitted in the Cardiothoracic Surgery Department of Al-Zahraa University Hospital from December 2019 to May 2020. All patients had received a diagnosis by CT chest and invasive method in the form of mediastinoscopy; then, histopathological results of the mediastinoscopic biopsy were correlated with the CT chest finding to estimate the relationship between both methods of diagnosis in cases with mediastinal lymphadenopathy. Results There is no definitive sign in CT imaging either using the size or shape or distribution to help in reaching the final diagnosis. Therefore, the biopsy is inevitable in all cases. Conclusion The CT remains the most important noninvasive tool for the diagnosis of mediastinal lymphadenopathies with good sensitivity, specificity, and diagnostic accuracy. Despite this, it does not exceed the prediction, and the cause of lymphadenopathy must be diagnosed to be able to start the appropriate treatment.
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纵隔淋巴结病的CT表现与纵隔镜活检结果的关系
背景纵隔病变很难在x线片上发现,因为这些病变是软组织密度的,并且被软组织结构包围。这就是计算机断层扫描(CT)可以提供答案的地方。它提供了病变的解剖范围和病变性质的信息。目的本研究的目的是评估在Al-Zahraa大学医院心胸外科收治的患者术前CT表现的基础上,通过纵隔镜检查获得的纵隔淋巴结病标本的组织病理学组织诊断的可能性。患者和方法本研究纳入了2019年12月至2020年5月在Al-Zahraa大学医院心胸外科收治的30例患者。所有患者均行胸部CT及纵隔镜有创检查诊断;然后,将纵隔镜活检的组织病理学结果与CT胸部检查结果进行对比,以评估两种诊断方法在纵隔淋巴结病病例中的关系。结果CT图像上没有明确的征象,无论是利用大小、形状或分布来帮助最终诊断。因此,活检在所有病例中都是不可避免的。结论CT具有良好的敏感性、特异性和诊断准确性,是诊断纵隔淋巴结病变最重要的无创工具。尽管如此,它并没有超出预测,淋巴结病的原因必须被诊断出来,才能开始适当的治疗。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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