Snake Envenomation in the Intensive Care Unit of a Tertiary Care Hospital, Dhaka, Bangladesh: A Prospective Cohort Study

S. K. Sarker, M. Salim, M. Hossain, B. Mandal
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引用次数: 1

Abstract

Background: Snake bite and the subsequent envenomation is an important health hazard which may lead to fatality in rural areas of Bangladesh. Objective: This study was conducted to evaluate the epidemiology, clinical profile, treatment and outcome for patients with snake bite admitted in the intensive care unit of Dhaka Medical College Hospital, Bangladesh. Methodology: This prospective cohort study was conducted in the Department of Anaesthesia, Analgesia, Palliative and Intensive Care Medicine, Dhaka Medical College, Dhaka, Bangladesh from May 2019 to April 2020 for a period one year. The patients of snake bite were treated in the Intensive care unit, Dhaka Medical College Hospital, Dhaka, Bangladesh. A questionnaire, containing information on bite, physical examination and identification of snake was used. Results: A total number of 23 patients of snake bite were treated in the Intensive care unit. Among the patients, 16 (69.56%) were bitten by cobra, 2 (8.6%) were suspected to be bitten by krait and 5(21.7%) cases had Russel viper bite. Tight tourniquet was used in 15(65.21%) cases. Among the patients 18(78.26%) patients were observed with the features of neurotoxicity with or without local envenoming. Among all patients, one patient required two doses of ASV, another patient needed 3 doses; but the other patients were found to be improved after getting a single dose of ASV. However, 15 patients needed ventilator support. The mean duration of ventilator support was 4.8 days. The mortality was 30.43% (7 patients). Out of these 7 patients, 4 patients died due to acute renal failure with DIC. Conclusion: Neuroparalytic Cobra envenomation is accounted for the highest incidence of venomous bites in the present study. Journal of Current and Advance Medical Research, January 2022;9(1):48-55
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孟加拉国达卡一家三级医院重症监护室的蛇中毒:一项前瞻性队列研究
背景:在孟加拉国农村地区,蛇咬伤和随后的中毒是一种重要的健康危害,可能导致死亡。目的:对孟加拉国达卡医学院附属医院重症监护室收治的蛇咬伤患者的流行病学、临床特点、治疗及转归进行分析。方法:这项前瞻性队列研究于2019年5月至2020年4月在孟加拉国达卡达卡医学院麻醉、镇痛、姑息和重症监护医学系进行,为期一年。蛇咬伤患者在孟加拉国达卡医学院医院重症监护室接受治疗。采用问卷调查法,对蛇的咬伤情况、体格检查和鉴定情况进行调查。结果:重症监护室共收治蛇咬伤患者23例。其中眼镜蛇咬伤16例(69.56%),金蛇咬伤2例(8.6%),拉塞尔毒蛇咬伤5例(21.7%)。使用严密止血带15例(65.21%)。18例(78.26%)患者有或无局部内源性神经毒性特征。在所有患者中,一名患者需要2剂ASV,另一名患者需要3剂;但其他患者在接受单剂量ASV后情况有所改善。然而,15例患者需要呼吸机支持。呼吸机支持的平均持续时间为4.8天。死亡率为30.43%(7例)。在这7例患者中,4例患者死于急性肾功能衰竭合并DIC。结论:神经麻痹性眼镜蛇中毒是本研究中毒蛇咬伤发生率最高的疾病。中华医学杂志,2022;9(1):48-55
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