{"title":"The microbial transformation of prostaglandins","authors":"M. Miyano, C. Dorn, F. Colton, W. J. Marsheck","doi":"10.1039/C29710000425","DOIUrl":null,"url":null,"abstract":"(±)-Δ8(12)-15-Dehydro-PGE1(III), (±)-Δ8(12)-PGE1(IV), and (±)-15-epi-Δ8(12)-PGE1(V) have been synthesized from the readily available starting material (I), and compound (III) has been stereoselectively reduced by micro-organisms to either (+)- or (–)-(V).","PeriodicalId":17278,"journal":{"name":"Journal of The Chemical Society D: Chemical Communications","volume":"9 1","pages":"425-425"},"PeriodicalIF":0.0000,"publicationDate":"1971-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of The Chemical Society D: Chemical Communications","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1039/C29710000425","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 12
Abstract
(±)-Δ8(12)-15-Dehydro-PGE1(III), (±)-Δ8(12)-PGE1(IV), and (±)-15-epi-Δ8(12)-PGE1(V) have been synthesized from the readily available starting material (I), and compound (III) has been stereoselectively reduced by micro-organisms to either (+)- or (–)-(V).
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