Thymoma with Myasthenia Gravis in Pregnancy: A Case Report

Rima Anggrena, Nurul Iftida, Amilia Afzan, M. Nazri, V. Velayudham
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Abstract

Thymoma is the commonest mediastinal tumour but a rare type of thymic tumour of unknown aetiology. The overall incidence of thymoma is 0.13 per 100,000 persons per year which is even rarer in pregnancy. Until this date, the specific link between thymoma and pregnancy has not been identified. Presentations are also variables and includes chest pain, respiratory insufficiency, superior vena cava syndrome or non-specific symptoms like fever and weight loss. An autoimmune paraneoplastic disease which is often linked with thymoma includes myasthenia gravis (MG), hypogammaglobinaemia, aplastic anaemia and systemic lupus erythematosus (SLE). Here we describe a case of thymoma in pregnancy who had successfully delivered and underwent surgical removal postpartum.      
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妊娠胸腺瘤合并重症肌无力1例
胸腺瘤是最常见的纵隔肿瘤,但也是一种罕见的胸腺肿瘤,病因不明。胸腺瘤的总发病率为每年每10万人中0.13人,在怀孕期间甚至更少。直到现在,胸腺瘤和怀孕之间的具体联系还没有被确定。表现也是可变的,包括胸痛、呼吸功能不全、上腔静脉综合征或发烧和体重减轻等非特异性症状。一种常与胸腺瘤相关的自身免疫性副肿瘤疾病包括重症肌无力(MG)、低γ -球蛋白血症、再生障碍性贫血和系统性红斑狼疮(SLE)。在这里我们描述一个胸腺瘤在怀孕谁成功分娩,并接受手术切除产后。
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