Wen-You Li , Zu-Hong Lu , Jin-Gou Xu , Xiang-Qun Guo , Qing-Zhi Zhu
{"title":"Spectroscopic study on the interaction between sodium 9,10-anthraquinone-2-sulfonate and DNA","authors":"Wen-You Li , Zu-Hong Lu , Jin-Gou Xu , Xiang-Qun Guo , Qing-Zhi Zhu","doi":"10.1016/S0968-5677(98)00116-3","DOIUrl":null,"url":null,"abstract":"<div><p>Sodium 9,10-anthraquinone-2-sulfonate (AQS) binds to the double helical DNA with a high affinity, as deduced from the absorption and fluorescence spectral data. The results of absorption spectra, KI quenching studies, competitive binding studies, and thermal denaturation experiments suggested the intercalative binding of AQS into DNA bases.</p></div>","PeriodicalId":22050,"journal":{"name":"Supramolecular Science","volume":"5 5","pages":"Pages 747-749"},"PeriodicalIF":0.0000,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/S0968-5677(98)00116-3","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Supramolecular Science","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0968567798001163","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Sodium 9,10-anthraquinone-2-sulfonate (AQS) binds to the double helical DNA with a high affinity, as deduced from the absorption and fluorescence spectral data. The results of absorption spectra, KI quenching studies, competitive binding studies, and thermal denaturation experiments suggested the intercalative binding of AQS into DNA bases.
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