VIETNAMESE Phellinus baumii FRUITING BODY, A POTENTIAL SOURCE OF ANTIOXIDANT AND α-AMYLASE INHIBITORY AGENTS

Abstract

n-Hexane, ethyl acetate, and butanol fractions from methanol extract of Vietnamese Phellinus baumii fruiting body consisted of phenolics, flavonoids, and terpenoids. Ethyl acetate and butanol fractions showed a high level of total phenolics. Ethyl acetate fractions possessed the highest phenolic content (532.96 ± 19.95 mg GAE\g), accounting for approximately 53% fraction dry weight. Free radical DPPH (1,1-diphenyl-2-picrylhydrazyl) scavenging capacity of all fractions correlated with their total phenolic content. Ethyl acetate fraction exhibited the strongest capacity with an IC50 value of 0.059 mg\mL, equivalent to nearly 50% of ascorbic acid’s capacity. Its ferric reducing power was off more than half of quercetin and acid ascorbic at the concentration of 0.2 mg\mL. Ethyl acetate also had remarkable α-amylase inhibitory activity (IC50= 0.38 mg\mL). The results suggested P. baumii fruiting body as a potent source for antioxidative and α-amylase inhibitory compounds.