Effect of argon laser before and after surgery on primary pterygium recurrence

Aya Abd-Elkhalak, S. Shalaby, Nermien Salah Mohammed
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Abstract

Background Pterygium is a common ocular surface lesion originating in the limbal conjunctiva. It has a high recurrence rate after excision; thus, there are multiple surgeries and adjuvant therapies to avoid this high recurrence rate. Aim The aim of this study is to demonstrate the effect of argon laser photocoagulation before and after surgery on primary pterygium recurrence. Patients and methods This study is a prospective interventional study that included a total of 20 eyes of 20 patients divided into two groups randomly: The follow-up period ranged between 6 and 15 months (mean: 10.5 months). Results The recurrence rate in group A was 20%, but in group B, it was 50%. However, it is still statistically insignificant (P=0.160); there was a highly significant difference between pterygium length on the cornea before and after treatment in recurrent cases in groups A and B, with shorter length in group A (P<0.01). Inflammatory signs and irritative symptoms resolved within 1–2 weeks in the two study groups, but it was faster in group A than in group B, with a statistically insignificant difference (P=0.196). Epithelial healing occurred within 1–2 weeks in the two study groups, but it was faster in group B than group A, with a statistically insignificant difference (P=0.673), and the mean time till recurrence was 7.5 months in group A and 7.8 months in group B, with a statistically insignificant difference (P=0.846). Conclusion Argon laser photocoagulation has benefits if used as adjuvant therapy to the bare sclera technique in pterygium excision as it decreases the recurrence rate. If recurrence occurs, the length of the recurrent pterygium on the cornea is less than the length preoperatively.
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氩激光手术前后对原发性翼状胬肉复发的影响
翼状胬肉是一种常见的眼表病变,起源于角膜缘结膜。术后复发率高;因此,需要多次手术和辅助治疗来避免这种高复发率。目的探讨氩气激光光凝术对原发性翼状胬肉术后复发的影响。患者与方法本研究为前瞻性介入研究,20例患者共20只眼,随机分为两组,随访时间6 ~ 15个月,平均10.5个月。结果A组复发率为20%,B组复发率为50%。但在统计学上仍不显著(P=0.160);a组和B组复发患者治疗前后角膜翼状胬肉长度差异极显著,a组翼状胬肉长度较短(P<0.01)。两组患者炎症体征及刺激性症状均在1 ~ 2周内消退,但A组较B组更快,差异无统计学意义(P=0.196)。两组患者上皮细胞愈合均在1 ~ 2周内完成,但B组愈合速度快于A组,差异有统计学意义(P=0.673); A组患者平均复发时间为7.5个月,B组患者平均复发时间为7.8个月,差异有统计学意义(P=0.846)。结论氩气激光光凝辅助巩膜光凝术治疗翼状胬肉具有降低复发率的优点。如果复发,角膜上复发翼状胬肉的长度小于术前的长度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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