[FOURNIER GANGRENE: AN ANALYSIS OF 15 CASES].

Q4 Medicine Japanese Journal of Urology Pub Date : 2021-04-20 DOI:10.5980/jpnjurol.112.65
A. Sakamoto, Tomoyuki Kaneko, A. Kanatani, Masaki Kimura, S. Takahashi, Yukio Yamada, Y. Miyake, T. Sakamoto, T. Nakagawa
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Abstract

(Objectives) This study aimed to evaluate the clinical characteristics and the mortality risk factors of 15 patients with Fournier gangrene in the past decade at Teikyo University Hospital. (Materials and methods) We retrospectively assessed 15 patients with Fournier gangrene between May 2009 and April 2019. We compared the demographic characteristics along with several clinical variables including Fournier Gangrene Severity Index of the survivors and nonsurvivors. We also assessed the risk factors associated with mortality. (Results) All patients were men with a median age of 67 years. Among the 15 patients, 9 had diabetes mellitus (60%). Furthermore, 14 patients (93%) underwent surgical debridement, 5 (33%) required orchiectomy, 3 (20%) were treated with cystostomy for urinary diversion, and 3 (20%) needed temporary colostomy for fecal diversion. Three patients died of the disease with a mortality rate of 20%. The nonsurvivors were significantly older (p = 0.043) and had a smaller body mass index (p = 0.038) than the survivors. The scores of clinical risk models, such as the Fournier Gangrene Severity Index, were higher in nonsurvivors than in survivors, with no statistical significance presumably due to the small sample size. (Conclusions) The mortality rate for Fournier gangrene during the past decade at our institution was 20%. Fournier gangrene was a potentially fatal disease even in the 2010s.
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[富尼尔坏疽15例分析]。
(目的)评价近十年来在东京大学医院收治的15例富尼耶坏疽患者的临床特点及死亡危险因素。(材料和方法)我们回顾性评估了2009年5月至2019年4月期间15例富尼耶坏疽患者。我们比较了幸存者和非幸存者的人口学特征以及一些临床变量,包括富尼耶坏疽严重程度指数。我们还评估了与死亡率相关的危险因素。(结果)所有患者均为男性,中位年龄67岁。15例患者中有糖尿病9例(60%)。此外,14例(93%)患者行手术清创,5例(33%)患者行睾丸切除术,3例(20%)患者行膀胱造口引流,3例(20%)患者行临时结肠造口引流。3名患者死于该病,死亡率为20%。非幸存者明显比幸存者年龄大(p = 0.043),体重指数也比幸存者小(p = 0.038)。临床风险模型的得分,如富尼耶坏疽严重程度指数,在非幸存者中高于幸存者,可能由于样本量小而没有统计学意义。(结论)我院近十年来富尼耶坏疽病死率为20%。即使在2010年代,富尼耶坏疽也是一种潜在的致命疾病。
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来源期刊
Japanese Journal of Urology
Japanese Journal of Urology Medicine-Urology
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