Biocompatibility of a magnesium coating on a titanium surface and its effects on BMSCs

IF 2.9 4区 材料科学 Q3 MATERIALS SCIENCE, MULTIDISCIPLINARY Materials Technology Pub Date : 2022-09-28 DOI:10.1080/10667857.2022.2129318
X. Ni, Quanming Zhao, Xiao-yun Pan, Gang Zhao, Xingyuan Zhu, Liu-bao Ren, Jiong Yu, Baisheng Cai, Jiyang Tan, Jingyi Mi
{"title":"Biocompatibility of a magnesium coating on a titanium surface and its effects on BMSCs","authors":"X. Ni, Quanming Zhao, Xiao-yun Pan, Gang Zhao, Xingyuan Zhu, Liu-bao Ren, Jiong Yu, Baisheng Cai, Jiyang Tan, Jingyi Mi","doi":"10.1080/10667857.2022.2129318","DOIUrl":null,"url":null,"abstract":"ABSTRACT Surface modification can effectively improve the biological activity of Ti, which is currently a popular research topic. In this study, we applied plasma electrolytic oxidation (PEO) technology to prepare a porous Mg-TiO2 coating on the surface of a Ti sheet. Then, we observed the adhesion and proliferation of bone marrow mesenchymal stem cells (BMSCs) on the surface of the Mg-TiO2 coating. The results showed that the Mg-TiO2 coating had a porous structure, and there was a uniform distribution of Mg on the surface and in the pores of the coating. The porous Mg-TiO2 coating showed good cytocompatibility and no obvious cytotoxicity. Significantly more BMSCs adhered to and proliferated on its surface than on pure Ti (p < 0.05). In conclusion, a Mg-TiO2 coating with a good surface morphology and good biocompatibility and bioactivity was prepared on a Ti surface by plasma technology and may have potential for clinical applications.","PeriodicalId":18270,"journal":{"name":"Materials Technology","volume":"86 1","pages":"3129 - 3139"},"PeriodicalIF":2.9000,"publicationDate":"2022-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Materials Technology","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1080/10667857.2022.2129318","RegionNum":4,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 1

Abstract

ABSTRACT Surface modification can effectively improve the biological activity of Ti, which is currently a popular research topic. In this study, we applied plasma electrolytic oxidation (PEO) technology to prepare a porous Mg-TiO2 coating on the surface of a Ti sheet. Then, we observed the adhesion and proliferation of bone marrow mesenchymal stem cells (BMSCs) on the surface of the Mg-TiO2 coating. The results showed that the Mg-TiO2 coating had a porous structure, and there was a uniform distribution of Mg on the surface and in the pores of the coating. The porous Mg-TiO2 coating showed good cytocompatibility and no obvious cytotoxicity. Significantly more BMSCs adhered to and proliferated on its surface than on pure Ti (p < 0.05). In conclusion, a Mg-TiO2 coating with a good surface morphology and good biocompatibility and bioactivity was prepared on a Ti surface by plasma technology and may have potential for clinical applications.
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
钛表面镁涂层的生物相容性及其对骨髓间充质干细胞的影响
摘要表面改性可以有效地提高钛的生物活性,是目前研究的热点。在这项研究中,我们应用等离子体电解氧化(PEO)技术在Ti片表面制备了多孔Mg-TiO2涂层。然后,我们观察骨髓间充质干细胞(BMSCs)在Mg-TiO2涂层表面的粘附和增殖。结果表明:Mg- tio2涂层具有多孔结构,Mg在涂层表面和孔隙中分布均匀。多孔Mg-TiO2涂层具有良好的细胞相容性,无明显的细胞毒性。BMSCs在其表面的粘附和增殖明显高于纯Ti表面(p < 0.05)。综上所述,通过等离子体技术在Ti表面制备了具有良好表面形貌、良好生物相容性和生物活性的Mg-TiO2涂层,具有潜在的临床应用价值。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 去求助
来源期刊
Materials Technology
Materials Technology 工程技术-材料科学:综合
CiteScore
6.00
自引率
9.70%
发文量
105
审稿时长
8.7 months
期刊介绍: Materials Technology: Advanced Performance Materials provides an international medium for the communication of progress in the field of functional materials (advanced materials in which composition, structure and surface are functionalised to confer specific, applications-oriented properties). The focus is on materials for biomedical, electronic, photonic and energy applications. Contributions should address the physical, chemical, or engineering sciences that underpin the design and application of these materials. The scientific and engineering aspects may include processing and structural characterisation from the micro- to nanoscale to achieve specific functionality.
期刊最新文献
Fabrication and development of biogenic selenium nanoparticles incorporated alginate hydrogel wound care material: a pre-clinical study Biopolymer-coated magnesium-alloy-based multi-functional bio-nanocomposite scaffolds Enhancing anticancer efficacy: xovoltib-loaded chitosan-tripolyphosphate nanoparticles for targeted drug delivery against MCF-7 breast cancer cells One Pot Synthesis, characterization, morphology and optical profilometry properties of La-doped and La–Ag-doped cobalt oxide nanoparticles Supercritical hydrothermal synthesis of ultra-fine Cu powders
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1