Aging of mesenchymal stem cells is a root cause of vascular calcification

Fang Xin, Siming Guan
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Abstract

We hypothesize that aging of mesenchymal stem cells breaking the balance between arterial mineral deposition and resorption results in vascular calcification. It is believed that it is a new idea about revealing pathogenesis of artery calcification and defining a range of novel and exciting therapeutic approaches.

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间充质干细胞老化是血管钙化的根本原因
我们推测,间充质干细胞的衰老打破了动脉矿物质沉积和吸收之间的平衡,导致血管钙化。认为这是揭示动脉钙化发病机制和确定一系列新颖而令人兴奋的治疗方法的新思路。
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