3B-4 Therapeutic Potential Metric for Diagnostic Transducers

K. Frinkley, S. Rosenzweig, K. Nightingale
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引用次数: 1

Abstract

The goal of this work is to develop a 'therapeutic potential' metric and experimental protocol to define the expected efficacy of commercial, diagnostic transducers for thermal therapy. Temperature rises at the transducer face were measured using thin-film thermocouples (TFTs) on a tissue mimicking phantom for sequences with moderate acoustic output as an indicator of the risk of damage to the transducer during therapeutic applications. Several measurements were then taken to evaluate the focal heating of the transducer and compared with thermocouple measurements. The acoustic power was measured near the surface of the transducer. Spatial peak and spatial average intensities were measured in the focal plane at low system voltages to avoid nonlinear effects. Finally, ARFI imaging displacements within plusmn25% of the focus in a tissue-mimicking phantom were evaluated. Four transducers were compared using these protocols (two curvilinear arrays, one phased array, and one two-dimensional array). Without focal gain considerations, acoustic power is an inaccurate predictor of focal heating. ARFI displacement cannot easily be used to estimate focal heating, primarily due to confounding mechanical phenomena. After normalizing each measurement by the ultrasound system input, measurement device properties, focal configuration, and temporal properties, the therapeutic potential metric can most efficiently and accurately be defined by maximizing the ratio of the spatial peak intensity at the focus to the heating at the transducer face. The ratio of spatial average intensity or temperature at the focus to surface temperature can be used as alternative or additional metrics. The ID, phased array was determined to have the highest therapeutic potential for focal depths near 3.75 cm.
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3B-4诊断传感器的治疗潜力度量
这项工作的目标是开发一种“治疗潜力”度量和实验方案,以定义用于热治疗的商用诊断换能器的预期功效。传感器表面的温升使用薄膜热电偶(TFTs)在组织模拟模体上测量,用于具有中等声学输出的序列,作为治疗应用期间传感器损坏风险的指标。然后采取一些测量来评估换能器的焦点加热,并与热电偶测量进行比较。声功率在换能器表面附近测量。为了避免非线性效应,在低系统电压下测量了焦平面的空间峰值和空间平均强度。最后,评估组织模拟幻影中超过25%的焦点内的ARFI成像位移。使用这些方案比较了四种换能器(两种曲线阵列,一种相控阵和一种二维阵列)。如果不考虑焦点增益,声功率就不能准确预测焦点加热。ARFI位移不容易用于估计焦点加热,主要是由于混淆的机械现象。在对超声系统输入、测量设备属性、焦点配置和时间属性进行归一化后,通过最大化焦点处空间峰值强度与换能器表面加热的比值,可以最有效、最准确地定义治疗电位度量。焦点处的空间平均强度或温度与表面温度的比率可以用作替代或附加的度量。相控阵在病灶深度3.75 cm附近具有最高的治疗潜力。
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