Experiences of Discrimination and Treatment Outcomes Among Pregnant and Postpartum People With Opioid Use Disorder [ID: 1376917]

Joyce H. Xu, E. Defranco, Aaron W Murnan, N. Nidey, M. Terplan, C. Wilder
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Abstract

INTRODUCTION: Experiences of discrimination among pregnant and postpartum people with opioid use disorder (OUD) are common and likely affect utilization of medication for OUD (MOUD), which is associated with reduced risk of overdose and death. We aimed to examine experiences of discrimination by prenatal care (PNC) and substance use disorder (SUD) treatment settings and estimate its effect on the risk of various MOUD utilization outcomes. METHODS: Patient-stakeholders co-designed survey questions to measure self-reported outcomes related to MOUD treatment utilization, return to substance use, and overdose. First, we examined the proportion of participants who endorsed items on a modified Healthcare Discrimination Scale and summed the total scores. Next, we quantified the effect of discrimination experienced by health care setting on postpartum MOUD utilization, return to use, and overdose using log-binomial models to calculate relative risk (RR) and 95% CIs. RESULTS: Among the 100 participants enrolled in the study, 57 reported experiencing discrimination, 56 within PNC and 33 within SUD treatment settings. Discrimination within PNC (RR 2.6, CI 1.06–6.40) and SUD treatment (RR 3.26, CI 1.59–6.70) were associated with increased risk of not using MOUD as prescribed. Discrimination within SUD treatment settings correlated with an increased risk of MOUD discontinuation (RR 2.56, CI 1.19–5.54) and return to use (RR 2.36, CI 1.18–4.73). CONCLUSION: Experiences of discrimination were common, especially within prenatal care settings, and discrimination was associated with poor MOUD treatment outcomes and risk of return to use. Interventions to address discrimination within health care settings can improve outcomes for pregnant and postpartum people with OUD.
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阿片类药物使用障碍孕妇及产后患者的歧视与治疗体会[j]
孕妇和产后阿片类药物使用障碍(OUD)患者的歧视经历是常见的,并且可能影响OUD (mod)药物的使用,这与过量使用和死亡风险降低有关。我们的目的是检查产前护理(PNC)和物质使用障碍(SUD)治疗设置的歧视经历,并估计其对各种mod使用结果风险的影响。方法:患者与利益相关者共同设计调查问题,测量与mod治疗利用、药物使用和过量相关的自我报告结果。首先,我们检查了在修订的医疗歧视量表上认可项目的参与者比例,并总结总分。接下来,我们使用对数二项模型来计算相对风险(RR)和95% ci,量化医疗环境对产后mod使用、返回使用和过量使用的影响。结果:在参加研究的100名参与者中,57人报告遭受歧视,56人在PNC治疗环境中,33人在SUD治疗环境中。PNC (RR 2.6, CI 1.06-6.40)和SUD治疗(RR 3.26, CI 1.59-6.70)中的歧视与未按规定使用mod的风险增加相关。SUD治疗设置中的歧视与mod停药(RR 2.56, CI 1.19-5.54)和重新使用(RR 2.36, CI 1.18-4.73)的风险增加相关。结论:歧视的经历是常见的,特别是在产前护理环境中,歧视与不良的mod治疗结果和再次使用的风险有关。解决卫生保健机构内歧视问题的干预措施可以改善孕妇和产后OUD患者的结局。
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