Concordance between clinical and histopathological diagnosis of intraosseous lesions in a reference center

Abstract

Objective: To evaluate the concordance between clinical and histopathological diagnosis of intraosseous lesions in individuals treated in a Reference Centre from 2006-2017. Material and Methods: A retrospective concordance study was conducted, reviewing the biopsy files and conclusive anatomopathological reports of intraosseous lesions. The collected data was analyzed in SPSS v10.0. The data were descriptively analysed obtaining the average age, gender frequency and most affected anatomical location. Cohen’s Kappa statistical test separately assessed the concordance between clinical and histopathological diagnoses of all intraosseous lesions and groups of cysts, tumours, and bone-associated lesions. All tests adopted a statistical significance level of 5%. Results: 255 biopsied lesions met the inclusion criteria. Most of the individuals were females (67.8%) in the third decade of life (20.8%) with a predominance of posterior mandibular lesions (42.4%). It was observed that concordance between the diagnoses of intraosseous lesions occurred in 66.7% of the treated cases (kappa = 0.475). The following rates were obtained: 63.3% for tumours (kappa = 0.171), 69.1% for lesions associated to bones (kappa = 0.242) and 66.7% for cysts (kappa = 0.233). Conclusion: Concordance of diagnoses of all intraosseous lesions was moderate (kappa= 0.475), being higher in the bone-associated lesions (reasonable kappa = 0.242) and lower in tumours (poor kappa = 0.171).