Restless Leg Syndrome in Hidradenitis Suppurativa Patients: A Cross-Sectional Study with Current Literature Review

Abstract

Aim: High frequencies of restless leg syndrome (RLS) have been reported in many dermatologic diseases like psoriasis and atopic dermatitis; however, its relationship with hidradenitis suppurativa (HS) is not clearly known. The aim of this study was to analyze the relationship between RLS and HS. Methods: The cases of HS admitted to the dermatology clinic from February 2021 to May 2021 were included in this cross-sectional study. The study included HS patients as well as an age-and sex-matched healthy control group. The patients were evaluated with Hurley clinical staging. Body mass index (BMI) and waist circumference were noted. Laboratory tests were performed. A diagnosis and severity assessment of Restless legs syndrome were made using the International RLS Study Group (IRLSSG) criteria and the IRLSSG severity scale, respectively. Results: A total of 40 patients with HS were enrolled in the study, with a control group of 99 healthy adults who were age and sex matched. The frequencies of RLS in the HS and control groups were 22.5% and 15.2%, respectively, and there was no statistically significant difference (p=0.43). Restless leg syndrome was rated as “very severe” in 55.6% of HS patients compared to 33.3% in the control group. There was no statistically significant difference in RLS severity among the groups (p=0.57). Conclusion: There was no increase in the frequency of RLS in HS patients.