{"title":"Advancements in high-resolution imaging of the iridocorneal angle.","authors":"Matthew J Keller, Thomas J Gast, Brett J King","doi":"10.3389/fopht.2023.1229670","DOIUrl":null,"url":null,"abstract":"<p><p>High-resolution imaging methods of the iridocorneal angle (ICA) will lead to enhanced understanding of aqueous humor outflow mechanisms and a characterization of the trabecular meshwork (TM) morphology at the cellular level will help to better understand glaucoma mechanics (e.g., cellular level biomechanics of the particulate glaucomas). This information will translate into immense clinical value, leading to more informed and customized treatment selection, and improved monitoring of procedural interventions that lower intraocular pressure (IOP). Given ICA anatomy, imaging modalities that yield intrinsic optical sectioning or 3D imaging capability will be useful to aid in the visualization of TM layers. This minireview examines advancements in imaging the ICA in high-resolution.</p>","PeriodicalId":14263,"journal":{"name":"International Journal of Numerical Methods for Heat & Fluid Flow","volume":"24 1","pages":"1229670"},"PeriodicalIF":5.1000,"publicationDate":"2023-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11182319/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Numerical Methods for Heat & Fluid Flow","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3389/fopht.2023.1229670","RegionNum":3,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2023/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"MATHEMATICS, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
High-resolution imaging methods of the iridocorneal angle (ICA) will lead to enhanced understanding of aqueous humor outflow mechanisms and a characterization of the trabecular meshwork (TM) morphology at the cellular level will help to better understand glaucoma mechanics (e.g., cellular level biomechanics of the particulate glaucomas). This information will translate into immense clinical value, leading to more informed and customized treatment selection, and improved monitoring of procedural interventions that lower intraocular pressure (IOP). Given ICA anatomy, imaging modalities that yield intrinsic optical sectioning or 3D imaging capability will be useful to aid in the visualization of TM layers. This minireview examines advancements in imaging the ICA in high-resolution.
期刊介绍:
The main objective of this international journal is to provide applied mathematicians, engineers and scientists engaged in computer-aided design and research in computational heat transfer and fluid dynamics, whether in academic institutions of industry, with timely and accessible information on the development, refinement and application of computer-based numerical techniques for solving problems in heat and fluid flow. - See more at: http://emeraldgrouppublishing.com/products/journals/journals.htm?id=hff#sthash.Kf80GRt8.dpuf