Advancements in high-resolution imaging of the iridocorneal angle.

IF 5.1 3区 工程技术 Q1 MATHEMATICS, INTERDISCIPLINARY APPLICATIONS International Journal of Numerical Methods for Heat & Fluid Flow Pub Date : 2023-08-21 eCollection Date: 2023-01-01 DOI:10.3389/fopht.2023.1229670
Matthew J Keller, Thomas J Gast, Brett J King
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Abstract

High-resolution imaging methods of the iridocorneal angle (ICA) will lead to enhanced understanding of aqueous humor outflow mechanisms and a characterization of the trabecular meshwork (TM) morphology at the cellular level will help to better understand glaucoma mechanics (e.g., cellular level biomechanics of the particulate glaucomas). This information will translate into immense clinical value, leading to more informed and customized treatment selection, and improved monitoring of procedural interventions that lower intraocular pressure (IOP). Given ICA anatomy, imaging modalities that yield intrinsic optical sectioning or 3D imaging capability will be useful to aid in the visualization of TM layers. This minireview examines advancements in imaging the ICA in high-resolution.

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虹膜角膜高分辨率成像的进展。
虹膜角膜(ICA)的高分辨率成像方法将有助于加深对房水外流机制的了解,而小梁网(TM)在细胞水平上的形态特征将有助于更好地了解青光眼的力学原理(如颗粒状青光眼的细胞水平生物力学)。这些信息将转化为巨大的临床价值,使治疗选择更加明智和个性化,并改善对降低眼内压(IOP)的手术干预的监测。鉴于 ICA 的解剖结构,能产生固有光学切片或三维成像功能的成像模式将有助于 TM 层的可视化。本微型视图将探讨 ICA 高分辨率成像的进展。
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来源期刊
CiteScore
9.50
自引率
11.90%
发文量
100
审稿时长
6-12 weeks
期刊介绍: The main objective of this international journal is to provide applied mathematicians, engineers and scientists engaged in computer-aided design and research in computational heat transfer and fluid dynamics, whether in academic institutions of industry, with timely and accessible information on the development, refinement and application of computer-based numerical techniques for solving problems in heat and fluid flow. - See more at: http://emeraldgrouppublishing.com/products/journals/journals.htm?id=hff#sthash.Kf80GRt8.dpuf
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