Advances in Simple and Chiral-HPLC Methods for Antiallergic Drugs and Chiral Recognition Mechanism

Analytica Pub Date : 2023-03-16 DOI:10.3390/analytica4010007
Imran Ali, Syed Dilshad Alam, R. Raja, S. Khan, Rushda Anjum, A. K. Jain, H. Aboul‐Enein, M. Locatelli
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引用次数: 1

Abstract

Among many diseases, allergy appears to be a serious problem for human beings. Various forms of allergic disorders make people tense, leading to some other health issues. Many medications, including nonracemic and racemic ones, are used to treat this problem. It is important to have exact analysis strategies just to see any medication side effects, plasma profiles, and working efficiency. Therefore, efforts are made to review simple and chiral HPLC methods for antiallergic drugs; HPLC is the best analytical technique. The highlights in this article include the world scenario, causes of allergy, the effect of allergy on the economy, the mechanism of allergy in humans, classes of antiallergic drugs, simple drugs, chiral drugs, analysis by HPLC, and the chiral recognition mechanism. Moreover, attempts are also made to highlight the management of allergies and future perspectives.
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抗过敏药物的简单手性高效液相色谱方法及手性识别机制研究进展
在许多疾病中,过敏似乎是困扰人类的一个严重问题。各种形式的过敏性疾病使人紧张,导致其他一些健康问题。许多药物,包括非外消旋和外消旋药物,都被用来治疗这个问题。重要的是要有准确的分析策略,以了解任何药物副作用,血浆谱和工作效率。因此,本文综述了抗过敏药物的简单和手性高效液相色谱方法;高效液相色谱法是最佳的分析技术。本文的重点内容包括世界情景、过敏的原因、过敏对经济的影响、人类过敏的机制、抗过敏药物的种类、简单药物、手性药物、高效液相色谱分析和手性识别机制。此外,还试图强调过敏的管理和未来的展望。
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