Comparison of efficacy between 577 nm micropulse laser and traditional laser retinal photocoagulation for the treatment of acute central serous chorioretinopathy

Abstract

Objective To compare the clinical efficacy between 577 nm micropulse laser and traditional laser retinal photocoagulation for the treatment of acute central serous chorioretinopathy (CSC). Methods Prospective clinical randomized controlled study.Fifty-four eyes of 45 cases diagnosed as acute CSC from Jul.2017 to Jun.2018 in the First Affiliated Hospital of Zhengzhou University were included in this study.Patients were randomly divided into two groups.Group A, 29 eyes of 23 cases, received 577 nm laser photocoagulation, and group B, 25 eyes of 22 cases, received traditional laser photocoagulation.The efficacy of the two groups were observed in followed up time. Results BCVA of two groups were improved at 1 and 3 months after treatment, and the difference was statistically significant between before and after treatment (P 0.05). In the last follow-up, the fundus examination and OCT showed no laser spot or damage of retinal pigment epithelium in group A, while 13 eyes (52.00%, 13/25) in the laser pigmentation change or slight pigment epithelial hyperplasia could be seen, and 6 eyes (24.00%, 6/25) on OCT local retinal pigment epithelial change or defect could be seen in group B. Conclusion Both 577 nm micropulse laser and traditional laser photocoagulation are effective for acute CSC, which can improve BCVA, reduce CMT and SRF.But the damage of 577 nm micropulse laser is slight. Key words: Chorioretinopathy, serous, central; Photocoagulation, laser; Efficacy