{"title":"Wound Healing Activity of Herbal Ointment Containing the Extracts of Hibiscus rosa-sinensis Flowers and Curcuma longa Rhizomes","authors":"F. Mustaffa, S. Parasuraman, G. Sahgal","doi":"10.5530/FRA.2020.2.15","DOIUrl":null,"url":null,"abstract":"Objectives: To evaluate wound healing activity of herbal ointment containing the extracts of Hibiscus rosa-sinensis flowers and Curcuma longa rhizomes. Methodology: H. rosa-sinensis flowers and C. longa rhizomes were extracted using 95% ethanol. H. rosa-sinensis and Hibiscus rosa-sinensis ointment were prepared using paraffin wax, lanolin and petroleum jelly. Ointment formulation was applied once daily on the excision wound made on Sprague Dawley rats for 20 days. Results: On day 20, the treatment group showed a significant increase in wound contraction which was 93.52 ± 1.38% when compared to control (87.62 ± 1.48%). Conclusion: Herbal ointment exhibited significant wound healing activity in rat excision wound model.","PeriodicalId":12388,"journal":{"name":"Free Radicals and Antioxidants","volume":"1 1","pages":"86-88"},"PeriodicalIF":0.0000,"publicationDate":"2021-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Free Radicals and Antioxidants","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5530/FRA.2020.2.15","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Objectives: To evaluate wound healing activity of herbal ointment containing the extracts of Hibiscus rosa-sinensis flowers and Curcuma longa rhizomes. Methodology: H. rosa-sinensis flowers and C. longa rhizomes were extracted using 95% ethanol. H. rosa-sinensis and Hibiscus rosa-sinensis ointment were prepared using paraffin wax, lanolin and petroleum jelly. Ointment formulation was applied once daily on the excision wound made on Sprague Dawley rats for 20 days. Results: On day 20, the treatment group showed a significant increase in wound contraction which was 93.52 ± 1.38% when compared to control (87.62 ± 1.48%). Conclusion: Herbal ointment exhibited significant wound healing activity in rat excision wound model.
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