Fuzzy-based dosage model of aqueous decoction of Adansonia digitata for the management of sickle cell anaemia patients in African Traditional Medicine

C. Agbonkhese, H. Soriyan, O. Oyelami
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Abstract

In recent time, fuzzy logic-based systems have been deployed in the area of orthodox medicine; especially in situations where precision is most valuable such as kidney transplant, diagnosis of ailments, drug prescription, etc. However, in the area of traditional medicine, no much attention has been given to its enhancement with the use of information technology especially in the area of herbal prescription. In this study, a fuzzy logic-based system is presented, which is used to simulate a prescription model for determining the precise herbal dose suitable for the management of patients suffering from Sickle Cell Disease (SCD). Data on the management of SCD patients were collected from forty Traditional Medical Practitioners (TMPs) at four different local government areas of Edo State, Nigeria. The mass of herb and volume of solvent were used as input parameters to design the dosage model, and simulated using MATLAB. The Fuzzy Inference System (FIS) results obtained for some patients were compared to the prescription given by the TMPs. The results show that the model will eliminate the ordeals of imprecision associated with the management of SCD patients in Nigeria using herbs. Keywords: African Traditional Medicine, Traditional Medicine, Traditional Medical Practitioners, Sickle Cell Disease, Fuzzy logic, Measurement
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非洲传统医学镰状细胞性贫血患者治疗中荆刺水煎剂的模糊剂量模型
近年来,基于模糊逻辑的系统在传统医学领域得到了广泛应用;特别是在精确是最重要的情况下,如肾脏移植,疾病诊断,药物处方等。然而,在传统医学领域,特别是在草药处方领域,人们对利用信息技术提高传统医学的重视程度并不高。在本研究中,提出了一个基于模糊逻辑的系统,用于模拟处方模型,以确定适合镰状细胞病(SCD)患者的精确草药剂量。从尼日利亚埃多州四个不同地方政府地区的40名传统医生(TMPs)收集了关于SCD患者管理的数据。以药材质量和溶剂体积为输入参数,设计了药量模型,并用MATLAB进行了仿真。将部分患者的模糊推理系统(FIS)结果与临床医生给出的处方进行比较。结果表明,该模型将消除与尼日利亚使用草药管理SCD患者相关的不精确问题。关键词:非洲传统医学,传统医学,传统医生,镰状细胞病,模糊逻辑,测量
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