Bactobilia Among Patients with Uncomplicated Cholelithiasis Undergoing Laparoscopic Cholecystectomy: The Risk Factors and Effects on Postoperative Infectious Complications

L. Ghahramani, Marzie Rezaeian Jahromi, G. Pouladfar, A. Bananzadeh, A. Safarpour, S. Hosseini, Manli Aminshahidi
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引用次数: 3

Abstract

Background: Determining the rate of bactibilia among patients under going laparoscopic cholecystectomy (LC) and its correla-tions with predisposing factors and postoperative infections, which help evaluate the need for prophylactic antibiotic. Methods: In this prospective study, 85 consecutive patients with uncomplicated cholelithiasis who underwent LC were enrolled from2012to2013. Routinebileculturewasdoneatthetimeof LC.Patientsweredividedinto2groups,1withnegativebilecultureand anotherwithbactibilia. Demographicandlaboratorydatawerecompared. Patientswerefollowedup10daysaftertheirlaparoscopy and 1 month after discharge to monitor the presence of infection. Results: Atotalof 7culturesof bilewerepositiveforbacteria(8.2%). Thepatients’ agewasthesolefactorwithasignificantrelation-ship with the rate of bactobilia (P = 0.016). Within 10 days after surgery, fever and surgical site infection were detected in 10.6% of patients, which was not significantly different in the 2 groups. There were no complications in the 30-day follow-up. Conclusions: Detectingbactobiliawithlowfrequencyandthelackof correlationbetweenbactobiliaandpostoperativeinfectious, complications did not support prescribing prophylactic antibiotic in respective patients. The older age was the sole predisposing factor for the development of bactobilia.
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腹腔镜胆囊切除术中无并发症胆石症患者的胆杆菌:危险因素及对术后感染并发症的影响
背景:了解腹腔镜胆囊切除术(LC)患者的菌群率及其与易感因素和术后感染的关系,有助于评估预防性使用抗生素的必要性。方法:在这项前瞻性研究中,从2012年到2013年,连续85例接受LC治疗的无并发症胆石症患者入组。Routinebileculturewasdoneatthetimeof LC。Patientsweredividedinto2groups 1 withnegativebilecultureand anotherwithbactibilia。Demographicandlaboratorydatawerecompared。在腹腔镜术后10天和出院后1个月对患者进行随访,以监测感染的存在。结果:7例胆汁培养细菌阳性(8.2%)。患者年龄是影响结核菌率的主要因素(P = 0.016)。术后10 d内发热及手术部位感染发生率为10.6%,两组比较差异无统计学意义。30天随访无并发症发生。结论:检出频率低且与术后感染、并发症无相关性,不支持相应患者预防性使用抗生素。年龄的增长是导致大肠杆菌增多的唯一因素。
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