Social Transfer of Fear in Rodents
Kacper Kondrakiewicz, Karolina Rokosz-Andraka, Tomasz Nikolaev, Tomasz Górkiewicz, Konrad Danielewski, Agata Gruszczyńska, Ksenia Meyza, Ewelina Knapska
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Abstract
Social transfer of fear is a potent tool facilitating response to danger in animals forming social groups. With many factors influencing the transfer—such as proximity of the animal receiving information to the donor, familiarity, proximity of danger, and species-specific coping strategies—it allows studies of neuronal correlates of a variety of behavioral responses. Since both the transfer of fear and social modulation of fear responses are impaired in many neuropsychological disorders, the models described in this article could be useful in disentangling the neuronal circuitry involved in the pathogenesis of these disorders. © 2019 by John Wiley & Sons, Inc.
Basic Protocol 1 : Imminent threat in rats
Alternate Protocol 1 : Imminent threat in mice
Basic Protocol 2 : Remote threat in rats
Alternate Protocol 2 : Remote threat in mice
Basic Protocol 3 : Social modulation of fear extinction in rats
Alternate Protocol 3 : Social modulation of fear extinction in mice
啮齿动物恐惧的社会转移
在形成社会群体的动物中,恐惧的社会转移是促进对危险反应的有力工具。由于有许多因素影响这种转移,例如动物接受信息的距离、熟悉程度、危险的距离和物种特有的应对策略,这使得研究各种行为反应的神经元相关性成为可能。由于恐惧的转移和恐惧反应的社会调节在许多神经心理障碍中都受到损害,本文中描述的模型可能有助于解开涉及这些疾病发病机制的神经回路。©2019 by John Wiley &基本协议1:小鼠的迫在眉睫的威胁替代协议1:小鼠的迫在眉睫的威胁基本协议2:小鼠的远程威胁替代协议2:小鼠的远程威胁基本协议3:小鼠恐惧消退的社会调节替代协议3:小鼠恐惧消退的社会调节
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