Role of ultrasound and doppler in characterizing thyroid nodules and differentiating benign and malignant thyroid nodules

Shubha N Rao, R. Dsouza, E. Saldanha, P. Joshua
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Abstract

One of the consequences of increased use of imaging has been the discovery of incidentalomas, or pseudodiseases, that are common in the general population but have no or minor clinical significance. One such incidentaloma, the thyroid nodule, is extremely common, found in some autopsy series in as much as 50% of the general population. Most thyroid nodules are benign, usually as a part of multinodular changes. Clinical examination is poor at detecting small thyroid nodules, highlighted by the fact that approximately 70% of clinically normal thyroid glands contain nodules of less than 1 cm when examined sonographically. The ultimate aim in the management of a thyroid nodule is to identify the small group of patients in whom the nodule is malignant and would benefit from early aggressive treatment while avoiding unnecessary investigation and surgery in the majority of patients who have a benign nodule. In view of the above said, we conducted this study to evaluate the diagnostic utility of ultrasound and doppler in characterizing thyroid nodules and differentiating benign and malignant thyroid nodules and correlation of this with the results of FNAC and or histopathology. A prospective study comparing FNAC and HPE on 110 patients was performed. Majority of our patients were in the age group of 40-49 years, predominant in females. Conclusion: FNAC sampling is a simple technique, which is easier to perform by the personnel and has better patient acceptability. FNA of thyroid is basically a technique that helps in differentiating lesions that require surgery from those can be managed conservatively. It can be used as initial modality in the evaluation of palpable thyroid nodules. But imaging also yields accuate results comapable to FNA.
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超声和多普勒在甲状腺结节特征及良恶性鉴别中的作用
影像学应用增加的后果之一是发现了偶发瘤或假性疾病,这些疾病在一般人群中很常见,但没有或很少有临床意义。其中一种偶发瘤,甲状腺结节,是非常常见的,在一些尸检系列中发现,在一般人群中高达50%。大多数甲状腺结节是良性的,通常是多结节病变的一部分。临床检查在发现小甲状腺结节方面很差,突出表现在超声检查时,约70%的临床正常甲状腺含有小于1厘米的结节。甲状腺结节治疗的最终目的是确定一小部分恶性结节患者,并从早期积极治疗中获益,同时避免对大多数良性结节患者进行不必要的检查和手术。鉴于以上所述,我们进行了这项研究,以评估超声和多普勒在甲状腺结节的特征和良恶性鉴别中的诊断价值,以及与FNAC和/或组织病理学结果的相关性。对110例患者的FNAC和HPE进行了前瞻性研究。大多数患者年龄在40-49岁之间,以女性为主。结论:FNAC取样技术操作简单,人员操作方便,患者接受度高。甲状腺的FNA基本上是一种技术,它有助于区分需要手术治疗的病变和那些可以保守治疗的病变。它可以作为评估可触及甲状腺结节的初始模式。但成像也能产生与FNA相媲美的准确结果。
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来源期刊
CiteScore
0.90
自引率
0.00%
发文量
226
审稿时长
3 months
期刊介绍: Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.
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