A. Ramkumar, X. Chen, D. Paduch, P.N. Schlegel, A. Lai
{"title":"Micro-Dissecting Dual-Probe Testicular Tubule Assay","authors":"A. Ramkumar, X. Chen, D. Paduch, P.N. Schlegel, A. Lai","doi":"10.1109/SENSOR.2007.4300544","DOIUrl":null,"url":null,"abstract":"We report on a microfabricated silicon probe integrated with an ultrasonic actuator and polysilicon strain gauges for Microdissection TEsticular Sperm Extraction (TESE) surgery. Insertion experiment was performed on rat testis tissue and by sensing the strain we were able to ascertain the size of the sperm-carrying microtubules in the sample. This information is important in Microdissection TESE to distinguish tubules with and without fertile sperm, eliminating large incision currently required for optical spermatazoa localization. Experimental data on tissue rigidity measurements indicate that the micromechanical assay can also be used for minimally-invasive testicular cancer detection.","PeriodicalId":23295,"journal":{"name":"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference","volume":"5 1","pages":"1959-1962"},"PeriodicalIF":0.0000,"publicationDate":"2007-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"TRANSDUCERS 2007 - 2007 International Solid-State Sensors, Actuators and Microsystems Conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/SENSOR.2007.4300544","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
We report on a microfabricated silicon probe integrated with an ultrasonic actuator and polysilicon strain gauges for Microdissection TEsticular Sperm Extraction (TESE) surgery. Insertion experiment was performed on rat testis tissue and by sensing the strain we were able to ascertain the size of the sperm-carrying microtubules in the sample. This information is important in Microdissection TESE to distinguish tubules with and without fertile sperm, eliminating large incision currently required for optical spermatazoa localization. Experimental data on tissue rigidity measurements indicate that the micromechanical assay can also be used for minimally-invasive testicular cancer detection.