CRISPR-Cas System: A Brief History and Future in the Diagnosis and Treatment of Infectious Diseases

B. Otlu
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引用次数: 1

Abstract

T he discovery of Clustered Regularly Interspaced Short Palindromic Repeat (CRISPR) and CRISPR-Associated System (Cas) have led to revolutionary advancements in almost every field of biology. The CRISPR-Cas system is part of an adaptive immune system in bacteria, and this system protects the organism from invading genetic elements of bacteriophages and plasmids. In this article, the discovery of the CRISPR-Cas system, its mechanism of action, and particularly its use in infectious diseases will be discussed.
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CRISPR-Cas系统:传染病诊断和治疗的简史和未来
聚类规则间隔短回文重复序列(CRISPR)和CRISPR相关系统(Cas)的发现几乎在生物学的每个领域都带来了革命性的进步。CRISPR-Cas系统是细菌适应性免疫系统的一部分,该系统保护生物体免受噬菌体和质粒遗传元素的入侵。本文将讨论CRISPR-Cas系统的发现及其作用机制,特别是其在传染病中的应用。
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