Kasumi Lee, Y. Oda, Masanobu Sakaguchi, Akihisa Yamamoto, C. Nishigori
{"title":"Drug‐induced photosensitivity to bicalutamide – case report and review of the literature","authors":"Kasumi Lee, Y. Oda, Masanobu Sakaguchi, Akihisa Yamamoto, C. Nishigori","doi":"10.1111/phpp.12230","DOIUrl":null,"url":null,"abstract":"Abstract Hormone therapy is highly important in the treatment of prostate cancer. Flutamide is used as an anti-androgen drug for prostate cancer; however, it has been reported that flutamide sometimes causes photosensitivity and severe liver dysfunction. In contrast, bicalutamide seldom causes these side-effects. Therefore, in recent years, flutamide has been replaced with bicalutamide as the most widely used anti-androgen drug for prostate cancer therapy. However, a few cases of photosensitivity caused by bicalutamide have been reported. Here, we present a case of photosensitivity caused by bicalutamide. This article is protected by copyright. All rights reserved.","PeriodicalId":20060,"journal":{"name":"Photodermatology","volume":"29 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2016-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Photodermatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1111/phpp.12230","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
Abstract
Abstract Hormone therapy is highly important in the treatment of prostate cancer. Flutamide is used as an anti-androgen drug for prostate cancer; however, it has been reported that flutamide sometimes causes photosensitivity and severe liver dysfunction. In contrast, bicalutamide seldom causes these side-effects. Therefore, in recent years, flutamide has been replaced with bicalutamide as the most widely used anti-androgen drug for prostate cancer therapy. However, a few cases of photosensitivity caused by bicalutamide have been reported. Here, we present a case of photosensitivity caused by bicalutamide. This article is protected by copyright. All rights reserved.
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