Novel Feature Representation and Machine Learning Methods in Computational Proteomics

IF 0.5 4区 生物学 Q4 BIOCHEMICAL RESEARCH METHODS Current Proteomics Pub Date : 2021-11-23 DOI:10.2174/157016461805210924161719
Lei Chen
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引用次数: 0

Abstract

In recent years, protein-related data have grown rapidly with the application of novel methods and techniques. Several online public databases have been set up, and investigators can easily retrieve various data reported in them. Traditional computational methods to deal with these data are becoming more and more inappropriate because they are in different forms. Thus, novel data-driven computational methods are increasingly needed. This thematic issue collects six excellent papers, out of which three papers reviewed newly proposed methods of essential problems in computational proteomics and three research articles proposed novel computational methods to deal with specific problems.
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计算蛋白质组学中的新特征表示和机器学习方法
近年来,随着新方法和新技术的应用,蛋白质相关数据迅速增长。已经建立了几个在线公共数据库,调查人员可以很容易地检索其中报告的各种数据。由于这些数据的形式不同,传统的计算方法越来越不适合处理这些数据。因此,越来越需要新的数据驱动的计算方法。本期专题收录了6篇优秀论文,其中3篇综述了计算蛋白质组学中关键问题的新方法,3篇研究论文提出了处理具体问题的新计算方法。
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来源期刊
Current Proteomics
Current Proteomics BIOCHEMICAL RESEARCH METHODS-BIOCHEMISTRY & MOLECULAR BIOLOGY
CiteScore
1.60
自引率
0.00%
发文量
25
审稿时长
>0 weeks
期刊介绍: Research in the emerging field of proteomics is growing at an extremely rapid rate. The principal aim of Current Proteomics is to publish well-timed in-depth/mini review articles in this fast-expanding area on topics relevant and significant to the development of proteomics. Current Proteomics is an essential journal for everyone involved in proteomics and related fields in both academia and industry. Current Proteomics publishes in-depth/mini review articles in all aspects of the fast-expanding field of proteomics. All areas of proteomics are covered together with the methodology, software, databases, technological advances and applications of proteomics, including functional proteomics. Diverse technologies covered include but are not limited to: Protein separation and characterization techniques 2-D gel electrophoresis and image analysis Techniques for protein expression profiling including mass spectrometry-based methods and algorithms for correlative database searching Determination of co-translational and post- translational modification of proteins Protein/peptide microarrays Biomolecular interaction analysis Analysis of protein complexes Yeast two-hybrid projects Protein-protein interaction (protein interactome) pathways and cell signaling networks Systems biology Proteome informatics (bioinformatics) Knowledge integration and management tools High-throughput protein structural studies (using mass spectrometry, nuclear magnetic resonance and X-ray crystallography) High-throughput computational methods for protein 3-D structure as well as function determination Robotics, nanotechnology, and microfluidics.
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