{"title":"Characterizing the sympatholytic role of endothelial‐dependent vasodilator signalling during handgrip exercise","authors":"Iain R Lamb, N. Novielli","doi":"10.1113/JP273806","DOIUrl":null,"url":null,"abstract":"The dynamic metabolic range of skeletal muscle necessitates an equally dynamic blood flow requirement, to the point where the demand for skeletal muscle blood flow during intense bouts of large muscle mass exercise can theoretically ‘outstrip’ the heart's ability to generate the cardiac output necessary for maintaining sufficient mean arterial pressure (MAP) and muscle perfusion. \n \nThis article is protected by copyright. All rights reserved","PeriodicalId":22512,"journal":{"name":"The Japanese journal of physiology","volume":"42 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2017-03-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"The Japanese journal of physiology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1113/JP273806","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
The dynamic metabolic range of skeletal muscle necessitates an equally dynamic blood flow requirement, to the point where the demand for skeletal muscle blood flow during intense bouts of large muscle mass exercise can theoretically ‘outstrip’ the heart's ability to generate the cardiac output necessary for maintaining sufficient mean arterial pressure (MAP) and muscle perfusion.
This article is protected by copyright. All rights reserved
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