Reconstrução tridimensional de artérias coronárias a partir da integração do ultrassom intracoronário e da angiografia convencional

Cristiano Guedes Bezerra , Gonzalo Daniel Maso Talou , Carlos Alberto Bulant , Breno de Alencar Araripe Falcão , José Mariani Jr. , Pablo Javier Blanco , Raúl Antonino Feijóo , Pedro Alves Lemos Neto
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Abstract

Background

Coronary three‐dimensional reconstruction with the combination of intravascular ultrasound and angiography offers advantages over computed tomography angiography of coronary arteries. The authors aimed to present the pilot phase of the validation of a new model of three‐dimensional reconstruction of coronary arteries.

Methods

This study used angiography and intravascular ultrasound examinations already performed by clinical indication in individuals with known or suspected stable coronary artery disease. Image processing, segmentation, and three‐dimensional reconstruction were conducted following specific methodology. For geometrical characterization purposes, tridimensional center lines were obtained.

Results

Three vessels were reconstructed: two left anterior descending arteries and one left circumflex artery. The vessel lumen volume and the overall plaque burden could be easily viewed with three‐dimensional reconstruction. The geometric characterization revealed increased absolute values of length, tortuosity, curvature, and torsion, featuring a greater complexity of the center line of the diseased lumen relative to the center line of the external elastic membrane.

Conclusions

This new methodology, which integrates conventional angiography and intravascular ultrasound, has increased the practicality of the reconstructions, with a gain in volumetric accuracy of the vessel and overall visualization of key aspects of atherosclerotic disease, such as plaque remodeling and distribution.

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冠状动脉内超声与常规血管造影相结合的冠状动脉三维重建
冠状动脉三维重建与血管内超声和血管造影相结合,比计算机断层扫描冠状动脉血管造影具有优势。作者的目的是提出验证冠状动脉三维重建新模型的试点阶段。方法本研究采用已知或疑似稳定型冠状动脉疾病患者经临床指征的血管造影和血管内超声检查。图像处理、分割和三维重建按照特定的方法进行。为了几何表征的目的,得到了三维中心线。结果重建了3条血管:2条左前降支和1条左旋支。通过三维重建可以很容易地观察到血管腔容量和斑块的总体负担。几何特征显示长度、扭曲度、曲率和扭转的绝对值增加,病变腔的中心线相对于外弹性膜的中心线具有更大的复杂性。这种新方法,结合了传统的血管造影和血管内超声,增加了重建的实用性,增加了血管体积的准确性和动脉粥样硬化疾病关键方面的整体可视化,如斑块重塑和分布。
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