Hyperthyroid crisis with cholestasis in a 12-year-old girl: a case report

IF 0.2 Q4 PEDIATRICS Paediatrica Indonesiana Pub Date : 2023-04-10 DOI:10.14238/pi63.2.2023.129-33
Celine Celine, N. Utami
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引用次数: 0

Abstract

Hyperthyroidism is considered to be an emergency in children. Death can occur in 10-20% of cases. This condition is found more often in adolescents and girls. Cholestasis may be caused by the hyperthyroidism or side effects of anti-thyroid drugs. Increased hepatic blood flow without adequate oxygen supply as a result of a hypermetabolic state affects the transport of bilirubin, leading to cholestasis.
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12岁女童甲状腺功能亢进合并胆汁淤积1例
甲状腺机能亢进被认为是儿童的急症。10-20%的病例可导致死亡。这种情况在青少年和女孩中更为常见。胆汁淤积可能是由甲状腺功能亢进或抗甲状腺药物的副作用引起的。由于高代谢状态导致的肝血流量增加,没有足够的氧气供应,影响胆红素的运输,导致胆汁淤积。
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CiteScore
0.40
自引率
0.00%
发文量
58
审稿时长
24 weeks
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