{"title":"Hyperthyroid crisis with cholestasis in a 12-year-old girl: a case report","authors":"Celine Celine, N. Utami","doi":"10.14238/pi63.2.2023.129-33","DOIUrl":null,"url":null,"abstract":"Hyperthyroidism is considered to be an emergency in children. Death can occur in 10-20% of cases. This condition is found more often in adolescents and girls. Cholestasis may be caused by the hyperthyroidism or side effects of anti-thyroid drugs. Increased hepatic blood flow without adequate oxygen supply as a result of a hypermetabolic state affects the transport of bilirubin, leading to cholestasis.","PeriodicalId":19660,"journal":{"name":"Paediatrica Indonesiana","volume":null,"pages":null},"PeriodicalIF":0.2000,"publicationDate":"2023-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Paediatrica Indonesiana","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.14238/pi63.2.2023.129-33","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"PEDIATRICS","Score":null,"Total":0}
引用次数: 0
Abstract
Hyperthyroidism is considered to be an emergency in children. Death can occur in 10-20% of cases. This condition is found more often in adolescents and girls. Cholestasis may be caused by the hyperthyroidism or side effects of anti-thyroid drugs. Increased hepatic blood flow without adequate oxygen supply as a result of a hypermetabolic state affects the transport of bilirubin, leading to cholestasis.
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