ChemInform Abstract: On the Search for Potential anti-Trypanosoma cruzi Drugs: Synthesis and Biological Evaluation of 2-Hydroxy-3-methylamino and 1,2,3-Triazolic Naphthoquinoidal Compounds Obtained by Click Chemistry Reactions.
{"title":"ChemInform Abstract: On the Search for Potential anti-Trypanosoma cruzi Drugs: Synthesis and Biological Evaluation of 2-Hydroxy-3-methylamino and 1,2,3-Triazolic Naphthoquinoidal Compounds Obtained by Click Chemistry Reactions.","authors":"Eufranio N. da Silva Junior, et al. et al.","doi":"10.1002/chin.201239148","DOIUrl":null,"url":null,"abstract":"<p>2-Hydroxy-3-substituted aminomethyl napthoquinones, napthoquinone-based triazoles (III) and (VI), nor-β-lapachone-based triazoles (VIII) and further lapachol derivatives are prepared and evaluated against the infective bloodstream form of T.cruzi.</p>","PeriodicalId":9834,"journal":{"name":"ChemInform","volume":"43 39","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2012-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1002/chin.201239148","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ChemInform","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/chin.201239148","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
2-Hydroxy-3-substituted aminomethyl napthoquinones, napthoquinone-based triazoles (III) and (VI), nor-β-lapachone-based triazoles (VIII) and further lapachol derivatives are prepared and evaluated against the infective bloodstream form of T.cruzi.