Binary Surfactant System for Preparation of Nano-Emulsion of Herbal Oil Mixtures

Usha, Ravikant
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Abstract

International Journal of Advanced Science and Engineering www.mahendrapublications.com ABSTRACT: In the present study, Nanoemulsions of neem oil and pine oil using a binary surfactant system were prepared and tested their antibacterial properties. A polysorbate-type nonionic surfactant and alcohol ethoxylatesurfactant (Galaxy MW-259) were used in different proportions to obtain stable nanoemulsions at the lowest possible droplet size. The emulsification process variables such as ratio of alcohol ethoxylatesurfactant to polysorbate-type nonionic surfactant, surfactant concentration, ratio of Neem oil to pine oil, oil weight fraction and sonication time were studied. The optimal variables include the ratio of alcohol ethoxylatesurfactant to polysorbate-type non-ionic surfactant of 80:20, surfactant concentration of 4%, ratio of Neem oil to pine oil of 80:20, oil weight fraction of 20% and 20 min of sonication time at 40% of the applied power. Nano-emulsions were found to be very stable with emulsion droplet size around 25-30 nm. The traditional method and probe sonicator methods are used for the preparation of oil in water Nano-emulsion of Neem oil, pine oil, a non-ionic binary surfactant system is used as an emulsifier. This newly developed nanoemulsion provides better antimicrobial, anti-bacterial and anti-mosquito repellent properties into the treated fabrics.
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二元表面活性剂体系制备中草药油混合纳米乳液
摘要:本研究采用二元表面活性剂体系制备了印楝油和松油的纳米乳液,并对其抗菌性能进行了测试。以聚山梨酯型非离子表面活性剂和乙醇-乙氧基酸酯表面活性剂(Galaxy MW-259)为原料,以不同的比例制备了稳定的纳米乳液。研究了醇乙氧基酸酯表面活性剂与聚山梨酯型非离子表面活性剂的比例、表面活性剂的浓度、印楝油与松油的比、油重分数和超声时间等乳化工艺参数。最佳参数为醇乙氧基酸酯类表面活性剂与聚山梨酯类非离子表面活性剂的比例为80:20,表面活性剂的浓度为4%,印楝油与松油的比例为80:20,油重分数为20%,在40%的功率下超声时间为20 min。纳米乳剂的稳定性非常好,乳剂的粒径在25-30纳米之间。采用传统方法和探针超声法制备印楝油、松油的水包油纳米乳液,采用非离子二元表面活性剂体系作为乳化剂。这种新开发的纳米乳液为处理后的织物提供了更好的抗菌、抗菌和防蚊性能。
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