Potential Effect of Dietary Vitamins A, C, and E, their Levels in Serum within Asthmatic Children

Gihan Ahmad, H. Abdel-Salam, Naglaa Mohammed Abd Alfattah, Magda Kostandy
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Abstract

he respiratory allergic ailment is an inflammatory condition joined by oxidative stress. Extra elements of anti-inflammatory factors such as antioxidants may have a curative effect. This study planned the status of vitamins (A, E &C) in food and sera of young some Egyptian children with allergic asthma coming to the National Nutrition Institute (NNI). The study inclsive104 children who attended the pediatric outpatient clinic of NNI during August and September 2014. The subjects in the study, both boys and girls, were randomly selected within the age range from 7-10 years. Asthma signs were assessed by a Chinese version of the International Study of Asthma and Allergies in Childhood (ISAAC) questionnaire. Data on nutritional status had been collected using specially designed questionnaires to cover required information on food intake (24-hour recall) and dietary pattern (food frequency) for chosen items. Body mass index was calculated based on the bodyweight within kilograms divided by the square of the body height in meters. After an overnight fast of 12 hours, blood samples of 5ml were collected from the children to determine serum levels of vitamin A, E, and C. The outcome revealed decreased daily intake and serum content from vitamin A, E, and C within asthmatic children parallel to normal children. Conclusion Despite the low level of intake antioxidants or there in serum within asthmatic children with no significant differences, they had signs of asthma, which confirms that the decrease in these vitamins, even a small amount, leads to asthma sensitivity.
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膳食维生素A、C和E对哮喘儿童血清水平的潜在影响
呼吸道过敏性疾病是一种由氧化应激引起的炎症。抗炎因子的额外元素,如抗氧化剂,可能有治疗效果。本研究计划了一些到国家营养研究所(NNI)就诊的埃及过敏性哮喘儿童的食物和血清中维生素(A, E和c)的状况。该研究纳入了2014年8月至9月期间在NNI儿科门诊就诊的104名儿童。这项研究的对象,男孩和女孩,都是随机选择的,年龄在7-10岁之间。采用中文版儿童哮喘与过敏国际研究(ISAAC)问卷评估哮喘体征。营养状况的数据是通过特别设计的问卷收集的,这些问卷涵盖了所选项目的食物摄入(24小时回忆)和饮食模式(食物频率)的必要信息。体重指数是以体重(以公斤为单位)除以身高(以米为单位)的平方来计算的。禁食12小时后,采集儿童5ml血样,测定血清中维生素A、E和C的水平。结果显示哮喘儿童每日维生素A、E和C的摄入量和血清中维生素A、E和C的含量与正常儿童相似。结论尽管哮喘儿童的抗氧化剂摄入水平低或血清中抗氧化剂含量无显著差异,但他们有哮喘的迹象,这证实了这些维生素的减少,即使是少量的,也会导致哮喘敏感性。
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