Alvimopan for post-operative ileus: What we should know?

Abhijit Nair
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引用次数: 11

Abstract

Alvimopan is an US-FDA approved, peripherally acting mu opioid receptor antagonist which when started pre-operatively has been shown to hasten intestinal motility and reduce the duration of post-operative ileus. However the logistics involved in procuring, storing and dispensing the drug and the cost of the drug for fifteen doses as approved by FDA prohibits the use of it on a regular basis.

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阿尔维莫泮治疗术后肠梗阻:我们应该知道些什么?
Alvimopan是一种美国fda批准的外周作用的mu阿片受体拮抗剂,术前开始使用该药物已被证明可加速肠道蠕动并缩短术后肠梗阻的持续时间。然而,采购、储存和分配药物所涉及的物流以及FDA批准的15剂药物的成本禁止定期使用。
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