{"title":"Notice of RetractionAquatic Predicted No-Effect Concentration (PNEC) Derivation for Perfluorooctane Sulfonic Acid (PFOA)","authors":"Wang Ying, J. Mu, Juying Wang","doi":"10.1109/ICBBE.2011.5781369","DOIUrl":null,"url":null,"abstract":"Perfluorooctanoic acid (PFOA), the representative perfluorinated surfactant, is an anthropogenic pollutant detected in various environmental matrices. Little is known regarding its safe thresholds to the aquatic ecosystem. Predicted no-effect concentrations (PNECs) for PFOA were derived based on the measured/predicted chronic/acute toxicity data. The interspecies correlation estimation (ICE) program and final acute-to-chronic ratio (FACR) were applied to investigate their capability for the derivation of PNEC. The recommended aquatic toxicity thresholds for PFOA are in the range of 0.30 ~ 8.48 mg/L. The ICE-based species sensitivity distribution (SSD) method has certain potential for the derivation of PNEC especially when toxicity data are limited.","PeriodicalId":6438,"journal":{"name":"2011 5th International Conference on Bioinformatics and Biomedical Engineering","volume":"17 1","pages":"1-4"},"PeriodicalIF":0.0000,"publicationDate":"2011-05-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"2011 5th International Conference on Bioinformatics and Biomedical Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/ICBBE.2011.5781369","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 2
Abstract
Perfluorooctanoic acid (PFOA), the representative perfluorinated surfactant, is an anthropogenic pollutant detected in various environmental matrices. Little is known regarding its safe thresholds to the aquatic ecosystem. Predicted no-effect concentrations (PNECs) for PFOA were derived based on the measured/predicted chronic/acute toxicity data. The interspecies correlation estimation (ICE) program and final acute-to-chronic ratio (FACR) were applied to investigate their capability for the derivation of PNEC. The recommended aquatic toxicity thresholds for PFOA are in the range of 0.30 ~ 8.48 mg/L. The ICE-based species sensitivity distribution (SSD) method has certain potential for the derivation of PNEC especially when toxicity data are limited.
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