Successful use of deep hypothermic circulatory arrest (DHCA) during mid-term pregnancy

Zachary Baker *, Scott Lick
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Abstract

Introduction

Ascending aortic dissection (Type A) often requires deep hypothermic circulatory arrest (DHCA) for proper repair. It involves the use of cardiopulmonary bypass to achieve whole body cooling to a temperature of 18 degrees Celsius prior to the cessation of all circulation. This circulatory arrest then allows for repair of the aortic arch and/or cerebral vessels without cross-clamp. This technique is well described and has become standard practice in the treatment of Type A dissection. The use of DHCA during pregnancy, however, has seldom been described.

Case description

A 31-year-old female at 21 weeks gestation presented acutely to the emergency department with a Type A aortic dissection. She was taken emergently to the operating room and cardiopulmonary bypass was initiated via femoral arterial and central venous cannulation. Aortic repair was accomplished during a 25 minute period of DHCA. Destruction of her aortic root by the dissection included the right coronary ostium and required composite tissue valve and conduit replacement (Bio–Bentall) with right coronary saphenous vein bypass. Fetal ultrasound imaging obtained preoperatively and postoperatively demonstrated no changes in fetal heart tones or obvious evidence of fetal injury. She was subsequently discharged on postoperative day 4. Evaluation by obstetrics 8 weeks postoperatively (29 weeks gestation) revealed normal fetal growth. 4 months post operatively she delivered a full-term infant without any noticeable deficits.

Conclusions

The use of DHCA for type A aortic dissection is standard practice but its use during pregnancy has rarely been described. This case illustrates the use of DHCA during midterm pregnancy that resulted in an excellent outcome.

Take home message

DHCA can successfully be used during midterm pregnancy.

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妊娠中期成功应用深度低温循环停搏(DHCA)
升主动脉夹层(A型)通常需要深度低温循环停搏(DHCA)来进行适当的修复。它包括使用体外循环在停止所有循环之前将全身冷却到18摄氏度。这种循环停止允许修复主动脉弓和/或脑血管而不需要交叉夹紧。这项技术被很好地描述,并已成为治疗A型夹层的标准做法。然而,怀孕期间DHCA的使用很少被描述。病例描述:一名31岁女性,妊娠21周,因a型主动脉夹层急诊科就诊。她被紧急送往手术室,并通过股动脉和中心静脉插管开始体外循环。主动脉修复在25分钟的DHCA期间完成。夹层破坏了她的主动脉根部,包括右冠状动脉开口,需要复合组织瓣膜和导管置换术(Bio-Bentall)并右冠状动脉隐静脉旁路。术前和术后获得的胎儿超声成像显示胎儿心脏音调未发生变化或胎儿损伤的明显证据。患者于术后第4天出院。术后8周(妊娠29周)产科检查显示胎儿生长正常。术后4个月生下足月婴儿,无明显缺陷。结论应用DHCA治疗A型主动脉夹层是标准做法,但其在妊娠期的应用鲜有报道。本病例说明了在中期妊娠期间使用DHCA可获得良好的结果。带回家的信息edhca可以成功地用于中期妊娠。
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