A Disease in Search for a Biomarker: MicroRNAs in Parkinson’s Disease

A. Chiş, A. Moatăr, I. Sîrbu
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Abstract

This review discusses the current research data on using microRNAs as biomarkers for the diagnostics and screening of Parkinson’s Disease (PD). We provide a comprehensive, critical analysis of the overwhelmingly diverse data on circulant microRNAs associated with PD. We also highlight the possible underlying molecular pathogenesis-related circulant microRNAs in the context of the natural history of PD.
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寻找生物标志物的疾病:帕金森病的microrna
本文综述了利用microrna作为帕金森病(PD)诊断和筛查生物标志物的研究进展。我们提供了一个全面的,批判性的分析与PD相关的循环microrna的压倒性多样化的数据。我们还强调了在PD的自然史背景下可能潜在的与分子发病相关的循环microrna。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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10
审稿时长
6 weeks
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