Mosquito Staging Apparatus for Producing PfSPZ Malaria Vaccines

2019 IEEE 15th International Conference on Automation Science and Engineering (CASE) Pub Date : 2019-08-01 DOI:10.1109/COASE.2019.8843147

Mengdi Xu, Shengnan Lyu, Yingtian Xu, Can Kocabalkanli, Brian K. Chirikjian, John S. Chirikjian, Joshua D. Davis, J. S. Kim, I. Iordachita, R. Taylor, G. Chirikjian

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引用次数: 5

Abstract

This paper describes the design of a fully automated apparatus to dispense mosquitoes into isolate units. This automation system consists of several process units including (1) facilitating the water vortex with a fan-shape rotor to gently transport the mosquitoes to the sorting slides with a conical geometry, (2) exploiting slides to guide mosquitoes to turntables driven by gears one by one, and (3) reorienting the mosquito until its proboscis points outward along the radial direction of the cone, aided by computer vision. This automation system serves as the first processing stage for collecting mosquito salivary glands. The sporozoites contained in the mosquito glands are the source material to produce Sanaria’s first generation PfSPZ vaccines. The Mosquito Staging System can dramatically enhance the mass production of Malaria Vaccine which is essential to prevent the propagation of Malaria.

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用于生产PfSPZ疟疾疫苗的蚊子分期装置

本文介绍了一种全自动蚊蝇分离装置的设计。该自动化系统由几个过程单元组成，包括:(1)利用扇形转子促进水涡流，将蚊子轻轻地输送到锥形的分选滑块上;(2)利用滑块将蚊子引导到一个接一个的齿轮驱动的转盘上;(3)在计算机视觉的辅助下，使蚊子重新定向，直到它的喙沿着圆锥体的径向指向外。该自动化系统是收集蚊子唾液腺的第一个处理阶段。蚊子腺体中含有的孢子虫是生产Sanaria第一代PfSPZ疫苗的来源材料。蚊子分期系统可以极大地促进疟疾疫苗的大规模生产，这对防止疟疾的传播至关重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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2019 IEEE 15th International Conference on Automation Science and Engineering (CASE)

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