{"title":"SYNTHESIS OF SOME BENZOTHIAZOLE ANILINE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITIES","authors":"Hoan Duong Quoc, Dung Nguyen Duc, Luong Truong Minh, Thao Nguyen Thi Thach, Hiền Nguyễn Thị Thu","doi":"10.18173/2354-1059.2022-0042","DOIUrl":null,"url":null,"abstract":"Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities.","PeriodicalId":17007,"journal":{"name":"Journal of Science Natural Science","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Science Natural Science","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.18173/2354-1059.2022-0042","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities.
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