A Rare Presentation of Neutrophilic Eccrine Hidradenitis in the Management of Acute Myeloid Leukaemia: A Case Report

Abstract

We present an unusual case of a 62-year-old male who was diagnosed with acute myeloid leukaemia and developed bilateral periocular skin dermatosis, concerning for neutrophilic eccrine hidradenitis, after receiving induction chemotherapy with Idarubicin and Cytarabine. On day seven of induction therapy, the patient developed swelling and discomfort around his right eye, which quickly progressed to involve the left side. Patient improved with supportive care with topical steroids and anti-inflammatory medications. Neutrophilic eccrine hidradenitis is typically a self-limited process. It does not appear to be associated with a worse prognosis for the underlying malignancy when occurring in that setting. The purpose of this report is to bring to light the importance of having a broad differential for dermal lesions in neutropenic patients and the avoidance of inappropriate therapy to prevent subsequent adverse events.