Surgical Treatment of Chronic Constrictive Pericarditis in a Developing Country

K. Souaga, E. Katché, Yoboua Aimé Kirioua-Kamenan, Jean Calaire Degré, K. A. Amani, Gnamien Randolph Niava, J. Kouame, Paul Yapo Yapo, K. Kendja
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Abstract

Background: Chronic constrictive pericarditis is a rare but serious clinical entity with a poor prognosis in the absence of surgical treatment. The purpose of this study was to report on our experience of subtotal anterior peri-cardectomy and analyze our surgical results. Results: We included 74 patients operated on for chronic constrictive pericarditis in our institution during the period from January 1985 to December 2020. There were 29 female and 45 male patients, with an average age of 28 years (range: 8 - 64 years). 36.5% of patients were in NYHA class III or IV. Physical signs were dominated by peripheral signs of right heart failure in 93.2% of cases. The surgical procedure was a subtotal anterior pericardectomy from the left to the right phrenic nerve, freeing the heart chambers and the large vessels. The surgical results were marked by a functional improvement in 82.4% of the cases. The post-operative complications were marked by a low cardiac output in 8.1% of the cases, a atrial fibrillation in 4.1% of the cases, a haemorrhage in 1.4% of the cases, a haemothorax in 2.7% of the cases. Perioperative mortality was 5.4% patients. The causes of death were low cardiac output in 50% of cases, hemorrhage in 25% of cases, and hepatocellular insufficiency in 25% of cases. We observed a mortality of 2.9% after an average follow-up of 5.17 years ± 4.76 years. All other survivors were asymptomatic and no re-intervention for recurrence was performed. Conclusions: Subtotal anterior pericardectomy was the technique we used for the treatment of chronic constrictive pericarditis. It allowed having satisfactory surgical results with a functional improvement and an acceptable morbidity.
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发展中国家慢性缩窄性心包炎的外科治疗
背景:慢性缩窄性心包炎是一种罕见但严重的临床疾病,在缺乏手术治疗的情况下预后较差。本研究的目的是报告我们的前心包次全切除术的经验,并分析我们的手术结果。结果:我们纳入了1985年1月至2020年12月在本院手术治疗慢性缩窄性心包炎的74例患者。女性29例,男性45例,平均年龄28岁(范围8 ~ 64岁)。36.5%的患者为NYHA III级或IV级。93.2%的患者以外周性右心衰体征为主。手术过程是前心包次全切,从左膈神经到右膈神经,释放心腔和大血管。82.4%的患者手术后功能得到改善。术后并发症的特点是8.1%的病例出现低心排血量,4.1%的病例出现心房颤动,1.4%的病例出现出血,2.7%的病例出现血胸。围手术期死亡率为5.4%。死亡原因为50%的病例心排血量低,25%的病例出血,25%的病例肝细胞功能不全。平均随访5.17年±4.76年,死亡率为2.9%。所有其他幸存者均无症状,未进行复发再干预。结论:前心包膜次全切术是治疗慢性缩窄性心包炎的有效方法。它允许在功能改善和可接受的发病率方面取得令人满意的手术结果。
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