The effect of herbal medicines on postpartum hemorrhage in Iran: A Meta-Analysis

Q3 Medicine Evidence Based Care Journal Pub Date : 2021-08-23 DOI:10.22038/EBCJ.2021.58054.2513

H. Moghaddam, Zahra Khojastehfard, M. Abdollahi, F. Karimi

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Abstract

Background: Postpartum hemorrhage is one of the most common causes of maternal mortality globally. Aim: In this systematic review and meta-analysis, we aim to evaluate the effectiveness of herbal medicines on postpartum hemorrhage. Methods: In this systematic review and meta-analysis, relevant articles from 2000 to 2020 were included using PubMed, Scopus, ISI Web of Science, Cochrane, Magiran, SID and Google Scholar databases. The relevant English keywords, "postpartum hemorrhage، PPH control, PPH prevention, phytotherapy, herbal medicine, complementary medicine, traditional medicine” were used to search for the eligible studies. Data analysis was done using STATA software version 11. Results: the result of the Meta-analysis indicatesthat there was heterogeneity in the studies (I2=0.87). Standardized mean difference was (SMD= -1.08, 95% CI: (-1.31, -0.85), p <0.001), (SMD= -0.80, 95% CI: (-1.03, -0.58), p <0.001), (SMD= -1.13, 95% CI: (-1.36, -0.90), p <0.001) in the first, second and third hour after delivery, respectively. There was a statistically significant difference between the control and intervention groups; as the bleeding rate was lower in the intervention group than the control group. Implications for Practice: This meta-analysis showed a positive role for the herbal medicines in reduce postpartum hemorrhage. Therefore, herbal medicine might be a proper substitute for chemical medicine and can be used in combination with pharmaceutical drugs such as oxytocin to reduce early postpartum hemorrhage

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中草药对伊朗产后出血的影响:荟萃分析

背景:产后出血是全球孕产妇死亡的最常见原因之一。目的:在本系统综述和荟萃分析中，我们旨在评估草药治疗产后出血的有效性。方法:采用PubMed、Scopus、ISI Web of Science、Cochrane、Magiran、SID和Google Scholar数据库，对2000 - 2020年的相关文献进行系统评价和meta分析。使用相关英文关键词“产后出血，PPH控制，PPH预防，植物疗法，草药，补充医学，传统医学”搜索符合条件的研究。数据分析采用STATA软件11版。结果:meta分析结果显示各研究存在异质性(I2=0.87)。标准化平均差异分别为(SMD= -1.08, 95% CI: (-1.31， -0.85)， p <0.001)， (SMD= -0.80, 95% CI: (-1.03， -0.58)， p <0.001)， (SMD= -1.13, 95% CI: (-1.36， -0.90)， p <0.001)分娩后第1、2、3小时。对照组和干预组之间的差异有统计学意义;干预组出血率明显低于对照组。实践意义:本荟萃分析显示草药在减少产后出血方面具有积极作用。因此，草药可能是化学药物的合适替代品，并可与催产素等药物联合使用，以减少产后早期出血

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Evidence Based Care Journal Medicine-Health Policy

CiteScore

2.00

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： The Evidence Based Care Journal (EBCJ) is an international, peer reviewed, scientific journal that seeks to promote the development and exchange of knowledge that is directly relevant to all spheres of patient care. The primary aim is to promote a high standard of clinically related scholarship which advances and supports patient care in practice. The Journal also aims to promote the international exchange of ideas and experience that draws from the different cultures in which practice takes place. Further, EBCJ seeks to enrich insight into clinical needs and the implications for patient care intervention and models of service delivery. Emphasis is placed on clinical practicality of research findings and strength of study design. EBCJ is essential reading for anyone involved in healthcare professions, whether clinicians, researchers, educators, managers, policy makers, or students. Contributions are welcomed from other health professionals on issues that have a direct impact on patient care.