Depression in Older Adults - A Review

IF 1.9 4区 医学 Q4 NEUROSCIENCES Restorative neurology and neuroscience Pub Date : 2023-03-30 DOI:10.33425/2692-7918.1044
Ke Zhou, S. Tan, Shiela P Arroyo, Si Ching Lim
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Abstract

The prevalence of major depressive disorder (MDD) is estimated to be 13.3%, while depressive symptoms are estimated to occur in 28.4% of older adults. A range of medical, functional, and psychosocial risk factors contribute to depression in this population. Depression in older adults may present differently than in younger adults with more physical complaints. Diagnosis becomes even more challenging in the presence of delirium and dementia, which often overlap in an older adult with MDD. It is important to assess suicide risks in older adults with depressive symptoms. Psychotherapy is recommended for mild to moderate depression, while antidepressants should be considered for severe depression or when psychotherapy is not available. Careful monitoring of side effects is important in older adults due to reduced physiological reserves.
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老年人抑郁症-综述
重度抑郁症(MDD)的患病率估计为13.3%,而抑郁症状估计发生在28.4%的老年人中。一系列的医疗、功能和社会心理风险因素导致了这一人群的抑郁症。老年人抑郁症的表现可能与年轻人不同,他们有更多的身体不适。在谵妄和痴呆的情况下,诊断变得更具挑战性,这在老年重度抑郁症患者中经常重叠。评估有抑郁症状的老年人的自杀风险很重要。轻度至中度抑郁症建议使用心理治疗,而重度抑郁症或心理治疗无效时应考虑使用抗抑郁药。由于生理储备减少,对老年人的副作用进行仔细监测很重要。
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来源期刊
CiteScore
5.40
自引率
3.60%
发文量
22
审稿时长
>12 weeks
期刊介绍: This interdisciplinary journal publishes papers relating to the plasticity and response of the nervous system to accidental or experimental injuries and their interventions, transplantation, neurodegenerative disorders and experimental strategies to improve regeneration or functional recovery and rehabilitation. Experimental and clinical research papers adopting fresh conceptual approaches are encouraged. The overriding criteria for publication are novelty, significant experimental or clinical relevance and interest to a multidisciplinary audience. Experiments on un-anesthetized animals should conform with the standards for the use of laboratory animals as established by the Institute of Laboratory Animal Resources, US National Academy of Sciences. Experiments in which paralytic agents are used must be justified. Patient identity should be concealed. All manuscripts are sent out for blind peer review to editorial board members or outside reviewers. Restorative Neurology and Neuroscience is a member of Neuroscience Peer Review Consortium.
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