İrem Akdemir-Kalkan1, Nejat Siraj Mohammed, G. Cınar, Ezgi Gülten, E. M. Saricaoğlu, Zeynep Ceren Kip-Karahan, A. M. Bozday, A. Azap
{"title":"Two cases of COVID-19 reinfection in Turkey","authors":"İrem Akdemir-Kalkan1, Nejat Siraj Mohammed, G. Cınar, Ezgi Gülten, E. M. Saricaoğlu, Zeynep Ceren Kip-Karahan, A. M. Bozday, A. Azap","doi":"10.36519/idcm.2021.59","DOIUrl":null,"url":null,"abstract":"It is not clear whether re-infection by SARS-CoV-2 occurs as a rare event or not, but since the start of the pandemic limited number of re-infection has been reported. This study reports the clinical presentations and comperative genome analysis of two patients who were suspected of re-infection. The patients showed mild clinical symptoms and varied antibody test results in the two episodes of infections. New generation sequencing of the isolates revealed the presence of different mutations between isolates from the previous and last infections. Therefore it is important to monitor these mutations and assess their capacity of evading previously occurred antibodies","PeriodicalId":11964,"journal":{"name":"European Journal of Clinical Microbiology and Infectious Diseases","volume":"130 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Clinical Microbiology and Infectious Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36519/idcm.2021.59","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
It is not clear whether re-infection by SARS-CoV-2 occurs as a rare event or not, but since the start of the pandemic limited number of re-infection has been reported. This study reports the clinical presentations and comperative genome analysis of two patients who were suspected of re-infection. The patients showed mild clinical symptoms and varied antibody test results in the two episodes of infections. New generation sequencing of the isolates revealed the presence of different mutations between isolates from the previous and last infections. Therefore it is important to monitor these mutations and assess their capacity of evading previously occurred antibodies