Biomarkers in Human and Environmental Health Risk Studies

Qasar Saleem, Tanveer Akbar, Aqsa Salamat
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Abstract

Uncertainties in human health risk assessment, and the measuring on the impacts of contaminants have attracted great concern. Uncertainties, source-to-outcome, exposure assessment, hazard and risk characterisations are a number of techniques that have been applied to maximize results. Experts’ opinions and quantitative tools have been applied to narrow the gap between data and rules for regulatory purposes. Bio monitoring information, in vitro data streams and computational toxicology are major areas for human health risk assessment. A need for a biomarkers data bank is of utmost need to minimize uncertainties in the toxicological environmental human health risk assessment field.
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人类和环境健康风险研究中的生物标志物
人类健康风险评估中的不确定性以及对污染物影响的测量引起了人们的极大关注。不确定性、来源到结果、暴露评估、危害和风险特征是为了最大限度地提高结果而应用的一些技术。专家的意见和量化工具已被应用于缩小数据与监管目的规则之间的差距。生物监测信息、体外数据流和计算毒理学是人类健康风险评估的主要领域。为了最大限度地减少毒理学环境人类健康风险评估领域的不确定性,迫切需要建立生物标志物数据库。
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