BioAlliance Pharma and Topotarget Agree to Merge and Combine Late-State Orphan Oncology Assets

Heather Cartwright
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Abstract

In a deal aimed at creating scale, France’s BioAlliance Pharma and Denmark’s Topotarget have agreed to combine their orphan oncology assets via a merger agreement. BioAlliance will be the continuing company and its shareholders will own approximately two-thirds of the combined entity. Topotarget’s sole asset is the pan-histone deacetylase (HDAC) inhibitor belinostat, which is awaiting a regulatory decision from the US FDA regarding its approval for the treatment of relapsed or refractory peripheral T-cell lymphoma. Belinostat will complement BioAlliance’s late-stage pipeline, which is led by Phase III Livatag® (doxorubicin Transdrug™) for advanced hepatocellular carcinoma.
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BioAlliance Pharma和Topotarget同意合并晚期孤儿肿瘤资产
在一项旨在扩大规模的交易中,法国的BioAlliance Pharma和丹麦的Topotarget已经同意通过合并协议合并他们的孤儿肿瘤资产。BioAlliance将继续运营,其股东将拥有合并后实体约三分之二的股份。Topotarget的唯一资产是泛组蛋白去乙酰化酶(HDAC)抑制剂belinostat,该药物正在等待美国FDA批准其用于治疗复发或难治性外周t细胞淋巴瘤的监管决定。Belinostat将补充BioAlliance的晚期产品线,该产品线由用于晚期肝细胞癌的III期Livatag®(doxorubicin Transdrug™)主导。
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