APPLICABILITY OF BIOMEDICAL PRODUCTS IN PATIENTS WITH DIABETIC FOOT SYNDROME

A. Kolke, E. Zinoviev, V. V. Zavatskiĭ
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引用次数: 1

Abstract

Fast and cost-effective treatment of patients with diabetic foot syndrome (DFS) is still a great challenge today. The use of biomedical cell products (BCP) in this category of patients has its own pathogenetic orientation, however, it remains not fully understood and accepted. This review presents the results of numerous studies confirming the effectiveness of the use of BCP for the treatment of mainly superficial trophic defects in patients with neuropathic form of DFS. However, these technologies are still behaved to adjuvant therapies. There are no clear algorithms and regulations for the use of BCP in patients with DFS. It was shown that use of BCP accelerates the reparative processes of superficial trophic defects in patients with neuropathic form of DFS in combination with standard therapy and reduces the time of wound epithelization. In view of the complexity and high cost of BCP, it should be considered the possibility of their use in patients with a neuroischemic form of DFS of different grades by WIfI classification.
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生物医药产品在糖尿病足综合征患者中的适用性
快速和具有成本效益的治疗糖尿病足综合征(DFS)患者今天仍然是一个巨大的挑战。在这类患者中使用生物医学细胞产品(BCP)有其自身的发病倾向,但尚未被完全理解和接受。这篇综述介绍了大量研究的结果,证实了BCP用于治疗神经病变型DFS患者主要是浅表营养缺陷的有效性。然而,这些技术仍然表现为辅助治疗。在DFS患者中使用BCP没有明确的算法和规定。研究表明,BCP与标准治疗联合使用可加速神经性DFS患者浅表营养缺陷的修复过程,并缩短创面上皮形成的时间。鉴于BCP的复杂性和高成本,应考虑其在不同WIfI分级的神经缺血性DFS患者中使用的可能性。
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来源期刊
Sklifosovsky Journal Emergency Medical Care
Sklifosovsky Journal Emergency Medical Care Medicine-Emergency Medicine
CiteScore
0.90
自引率
0.00%
发文量
83
审稿时长
8 weeks
期刊介绍: The Journal "Neotlozhnaia meditsinskaia pomoshch" (parallel titles: Zhurnal im. N.V. Sklifosovskogo "Neotlozhnai︠a︡ medit︠s︡inskai︠a︡ pomoshch", "Sklifosovsky Journal of Emergency Medical Care") seeks to publish original research articles, literature reviews, case reports, brief reports on clinical practice, and other suitable material submitted by professionals involved in the diagnosis and treatment of acute medical and surgical conditions.
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