Uterine artery pulsatility index among polycystic ovary disease; case control study

Abstract

     Introduction: Polycystic ovarian syndrome is a multiple organ disorder affects 5 to 10 % female population. The world occurrence of PCOS is 105 million in the age ranges from 15 to 45. The polycystic ovarian syndrome is a set of disorders like amenorrhea, infertility, polycystic ovaries, hyperinsulinemia, hirsutism, acne vulgaris and other symptoms of hyperandrogenism. Color Doppler and Pulse Doppler play a major role in evaluation of uterine artery Resistive index for access correlation with PCOS. PCOS patients suffer from primary and secondary infertility. This study aimed to show assess uterine blood flow and whether there is a correlation between these patterns and specific hormonal parameters. A case control study done in Salah Al-Deen governorate during the period of 1st May–1st October 2022. Twenty-five patients with polycystic ovary disease compared with 25 normal healthy women. The ultrasound and Doppler analyses were performed for all women during the follicular phase of the menstrual cycle. Uterine artery blood flow velocities were analyzed and the pulsatility index, were calculated. The current study showed that oligomenorrhea found among (72%) of the patients, clinical/biochemical signs of hyperandrogenism found among (76%). The mean LH (mIU/L) was significantly higher among PCO disease cases and also that the mean FSH (mIU/L) was significantly lower among PCO disease cases  than control group. There was at increased ovarian volume of > 10 cm3 found among (80%), and ≥12 follicles measuring 2-9 mm found in (84%) of the PCO disease patients. The mean Uterine artery PI was significantly higher among PCO disease cases 2.3 ± 0.5 than control group 1.8 ± 0.4 (P value <0.05). The mean ovarian volume was significantly higher among PCO disease cases  than control group. The mean Uterine artery PI was significantly higher among PCO disease cases than control group.