Meningitis aguda por Listeria monocytogenes en paciente con hemocromatosis hereditaria y colitis ulcerosa en tratamiento con infliximab

Abstract

Hereditary haemochromatosis (HH) is an autosomal recessive genetic disease related to iron overload due to a mutation of the HFE gene located in chromosome 6. This chromosome is located on locus HL-DR, which is the same as ulcerative colitis. This could mean that patients who have HH have a greater predisposition to suffer an inflammatory bowel disease. In addition, both diseases increase the risk of infections by intracellular bacteria, such as Listeria monocytogenes.